Please use this identifier to cite or link to this item: http://repositorio.unicamp.br/jspui/handle/REPOSIP/57477
Type: Artigo de periódico
Title: Crystallization and preliminary X-ray diffraction studies of piratoxin II, a phospholipase A(2) isolated from the venom of Bothrops pirajai
Author: Lee, WH
Goncalez, MC
Ramalheira, RMF
Kuser, PR
Toyama, MH
Oliveira, B
Giglio, JR
Marangoni, S
Polikarpov, I
Abstract: The phospholipases A(2) (PLA(2), E.C. 3.1.1.4, phosphatide sn2 acylhydrolases) are the major components of the venom of several snakes. They are responsible for several important pharmacological effects observed in ophidian incidents. PLA(2) piratoxin II from Bothrops pirajai has been crystallized by the vapour-diffusion technique. X-ray diffraction data have been collected to 2.04 Angstrom resolution (90.2% complete, R-merge = 0.070). The space group is P2(1) and the cell parameters are a = 46.19, b = 60.36, c = 58.74 Angstrom and beta = 96.05 degrees. re structure has been solved by molecular replacement using the crystallographic structure of PLA(2) from Bothrops asper (PDB code 1CLP) as a search model.
Country: Dinamarca
Editor: Munksgaard Int Publ Ltd
Rights: aberto
Identifier DOI: 10.1107/S0907444998007082
Date Issue: 1998
Appears in Collections:Unicamp - Artigos e Outros Documentos

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