Please use this identifier to cite or link to this item: http://repositorio.unicamp.br/jspui/handle/REPOSIP/57469
Type: Artigo de periódico
Title: Crystallization and preliminary diffraction data of neurotoxin Ts-gamma from the venom of the scorpion Tityus serrulatus
Author: Golubev, AM
Lee, WH
Marangoni, S
Novello, JC
Oliveira, B
Toyama, MH
Polikarpov, I
Abstract: Scorpion neurotoxin Ts-gamma was isolated from Tityus serrulatus venom and purified to apparent homogeneity by ion-exchange HPLC. Crystals of the toxin were grown using polyethylene glycol 6000 as precipitant and were found to belong to the monoclinic space group P2(1) with cell parameters a = 22.20, b = 36.90, c = 31.57 Angstrom, beta = 100.85 degrees. The crystals diffract beyond 1.73 Angstrom resolution at a synchrotron beamline, being notably stable during X-ray exposure. The structure has been solved by molecular replacement using the very high resolution structure of Sahara scorpion Androctonus australis Hector (PDB code 1AHO) as a search model.
Country: Dinamarca
Editor: Munksgaard Int Publ Ltd
Rights: aberto
Identifier DOI: 10.1107/S0907444998007197
Date Issue: 1998
Appears in Collections:Unicamp - Artigos e Outros Documentos

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