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Type: Artigo de periódico
Title: CPAP at 10 cm H(2)O during cardiopulmonary bypass does not improve postoperative gas exchange
Author: de Figueiredo, LC
Araujo, S
Abdala, RCS
Abdala, A
Guedes, CAV
Abstract: Objective: To compare postoperative (PO) pulmonary gas exchange indexes in patients submitted to myocardial revascularization (MR) with or without the application of continuous positive airway pressure (CPAP) during cardiopulmonary bypass (CPB). Methods: Thirty adult patients submitted to MR with CPB between March and September 2005 were randomly allocated to two groups: CPAP (n=15), patients that received CPAP at 10 cmH(2)O during CPB, and control (n=15), patients that didn't receive CPAP. PaO(2)/FiO(2) and P(A-a)O(2) were analyzed at four moments: Pre dust before CPB, with FiO(2)=1.0); Post (30min post-CPB, with FiO(2)=1.0); immediate PO period (12h post-surgery, with FiO(2)=6.4 by using a Venturi (R) facial mask) and first PO day (24h post-surgery, with FiO(2)=0.5 by a facial mask). Results: PaO(2)/FiO(2) and P(A-a)O(2) tend to get significantly worst as time elapsed during the postoperative period in both groups, but no differences were observed between them at any moment. When PaO(2)/FiO(2) was subdivided into three categories, a greater prevalence of patients with values between 200 mmHg and 300mmHg were observed in CPAP group only at moment Post (30min post-CPB; p = 0.02). Conclusion: CPAP at 10cmH2O administered during CPB, although had lightly improved PaO(2)/FiO(2) at 30 minutes post-CPB, had no significant sustained effect on postoperative pulmonary gas exchange. We concluded that in patients submitted to MR, application of 10 cmH(2)O CPAP does not improve postoperative pulmonary gas exchange.
Subject: Continuous positive airway pressure
Extracorporeal circulation
Pulmonary gas exchange
Cardiac surgical procedures
Country: Brasil
Editor: Soc Brasil Cirurgia Cardiovasc
Rights: aberto
Date Issue: 2008
Appears in Collections:Unicamp - Artigos e Outros Documentos

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