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Type: Artigo de periódico
Title: Minimal inhibitory concentration (MIC) determination of disinfectant and/or sterilizing agents
Author: Mazzola, PG
Jozala, AF
Novaes, LCD
Moriel, P
Penna, TCV
Abstract: Due to the growing number Of Outbreaks of infection in hospital and nurseries, it becomes essential to set up a sanitation program that indicates that the appropriate chemical agent was chosen for application in the most effective way. Validating the effectiveness of decontamination and disinfection is ail important and often challenging task. In order to study and compare the behavior of selected microorganisms, they Were Submitted to minimal inhibitory concentration (MIC). The MIC intervals, which reduced bacteria Populations over 6 log10, were: 59 to 156 mg/L of quaternary ammonium compounds (QACs)- 63 to 10000 mg/L of chlorhexidine; 1375 to 3250 mg/L of glutaraldehyde; 39 to 246 mg/L of formaldehyde; 43750 to 87500 mg/L of ethanol; 1250 to 6250 mg/L of iodine in polyvinyl-pyrolidone complexes, 150 to 4491 mg/L of chlorine-releasing-agents (CRAs) and 469 to 2500 mg/L of hydrogen pet-oxide. Chlorhexidine showed non inhibitory activity over germinating spores. A. calcoaceticus showed resistance to the majority of the agents tested, followed by E. cloacae and S. marcescens.
Subject: Minimal inhibitory concentration
Disinfectant agents
Sterilizing agents
Country: Brasil
Editor: Univ Sao Paulo, Conjunto Quimicas
Rights: aberto
Date Issue: 2009
Appears in Collections:Artigos e Materiais de Revistas Científicas - Unicamp

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