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Type: Artigo de periódico
Title: Connective Tissue Reaction of Rats to a New Zinc-Oxide-Eugenol Endodontic Sealer
Author: Triches, KM
Simi, J
Calixto, JB
Machado, R
Rosa, TP
Silva, EJNL
Vansan, LP
Abstract: The aim of this study was to evaluate the biocompatibility in rat subcutaneous connective tissue of a new zinc oxide endodontic sealer (Endomethasone N) compared to those provided by Endofill and Sealer 26. Polyethylene tubes containing the test materials were implanted into dorsal subcutaneous connective tissue of Wistar albino rats. After 7 and 42 days, the implants with the surrounding tissue were collected, fixed, and processed for histologic evaluation. Sections were evaluated for the presence of inflammatory cells (poly or monomorfonuclear), blood vessels, necrosis area, and thickness of fibrous capsule. Comparisons between groups and time-periods were performed with Kruskal-Wallis and Mann-Whitney U non-parametric tests for 5% significance level. No differences in the biocompatibility patterns among the materials for the 2 experimental periods were observed. Independently of the sealer, the tissue behavior showed a tendency to decrease the irritation effect over time. It can be concluded that all sealers are irritant, but its toxicity decreased with time. Endomethasone N showed biocompatible characteristics comparable with those provided by Endofill and Sealer 26. Microsc. Res. Tech. 76:1292-1296, 2013. (c) 2013 Wiley Periodicals, Inc.
Subject: Endomethasone N
root canal sealer
Country: EUA
Editor: Wiley-blackwell
Rights: fechado
Identifier DOI: 10.1002/jemt.22299
Date Issue: 2013
Appears in Collections:Artigos e Materiais de Revistas Científicas - Unicamp

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