Please use this identifier to cite or link to this item:
|Type:||Artigo de periódico|
|Title:||Metal carbene N-H insertion of chiral alpha,alpha '-dialkyl alpha-diazoketones. A novel and concise method for the stereocontrolled synthesis of fully substituted azetidines|
|Abstract:||The syntheses of all cis substituted azetidines were accomplished in few steps from L-serine in modest to high yields. The key step was based on a rhodium or copper carbenoid N-H insertion of alpha,alpha'-dialkyl-alpha-diazoketones to furnish cis-2,4-dialkyl-azetidin-3-ones as the only observable diastereoisomers. (C) 2004 Elsevier Ltd. All rights reserved.|
|Editor:||Pergamon-elsevier Science Ltd|
|Appears in Collections:||Unicamp - Artigos e Outros Documentos|
Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.