Please use this identifier to cite or link to this item: http://repositorio.unicamp.br/jspui/handle/REPOSIP/55894
Type: Artigo de periódico
Title: Chronic Exercise Promotes Alterations in the Neuroendocrine Profile of Elderly People
Author: Alves, ES
Souza, HS
Rosa, JPP
Lira, FS
Pimentel, GD
Santos, RVT
Oyama, LM
Damaso, AR
do Nascimento, CMO
Viana, VAR
Boscolo, RA
Grassmann, V
Santana, MG
Tufik, S
de Mello, MT
Abstract: Aging and physical inactivity are 2 factors that favour the development of cardiovascular disease, metabolic syndrome, obesity, and diabetes. In contrast, adopting a habitual moderate exercise routine may be a nonpharmacological treatment alternative for neuroendocrine aging disorders. We aimed to assess the effects of moderate exercise training on the metabolic profiles of elderly people with sedentary lifestyles. Fourteen sedentary, healthy, elderly male volunteers participated in a moderate training regimen for 60 min/day, 3 days/week for 24 weeks at a work rate equivalent to their ventilatory aerobic threshold. The environment was maintained at a temperature of 23 +/- 2 degrees C, with a humidity of 60 +/- 5 %. Blood samples for analysis were collected at 3 intervals: at baseline (1 week before training began), and 3 and 6 months after training. The training promoted increased aerobic capacity (relative VO2, and time and velocity to VO(2)max; (p < 0.05)) and reduced serum alpha-MSH (p < 0.05) after 3 months of training when compared with the baseline data. In addition, serum thyroid hormone (T3 and T4) was reduced after 6 months of training compared with baseline levels. Our results demonstrate that a moderate exercise training protocol improves the metabolic profile of older people, and metabolic adaptation is dependent on time.
Subject: aerobic capacity
neuropeptides
aging
moderate training
Country: Alemanha
Editor: Georg Thieme Verlag Kg
Rights: aberto
Identifier DOI: 10.1055/s-0032-1316294
Date Issue: 2012
Appears in Collections:Artigos e Materiais de Revistas Científicas - Unicamp

Files in This Item:
File Description SizeFormat 
WOS000312501800008.pdf201.81 kBAdobe PDFView/Open


Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.