Please use this identifier to cite or link to this item: http://repositorio.unicamp.br/jspui/handle/REPOSIP/55534
Type: Artigo de periódico
Title: BIOCHEMICAL-CHARACTERIZATION OF A VASCULAR SMOOTH-MUSCLE CONTRACTING POLYPEPTIDE PURIFIED FROM PHONEUTRIA-NIGRIVENTER (ARMED SPIDER) VENOM
Author: MARANGONI, S
BORGES, NCC
MARANGONI, RA
ANTUNES, E
VIEIRA, CA
NOVELLO, JC
DOMONT, GB
GIGLIO, JR
OLIVEIRA, B
DENUCCI, G
Abstract: Crude Phoneutria nigriventer venom was fractionated by Sephadex, ion-exchange and reverse-phase high performance liquid chromatography. One protein (PNV1) with spasmogenic activity in rabbit vascular smooth muscle was isolated and biochemically characterized. PNV1 has 125 amino acid residues and a calculated mol. wt of 13,899. Special features of the amino acid composition of PNV1 are the presence of two disulfide bridges and the high percentage (27%) of Asx and Glx. The N-terminal amino acid sequence indicates that PNV1 is different from other polypeptides isolated from Phoneutria nigriventer venom.
Country: Inglaterra
Editor: Pergamon-elsevier Science Ltd
Rights: fechado
Identifier DOI: 10.1016/0041-0101(93)90173-G
Date Issue: 1993
Appears in Collections:Artigos e Materiais de Revistas Científicas - Unicamp

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