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Type: Artigo de periódico
Title: Benign mesial temporal lobe epilepsy
Author: Labate, A
Gambardella, A
Andermann, E
Aguglia, U
Cendes, F
Berkovic, SF
Andermann, F
Abstract: Benign mesial temporal lobe epilepsy (bMTLE), which is defined as at least 24 months of seizure freedom with or without antiepileptic medication, has probably been under-recognized because of a literature bias toward refractory epilepsy cases. Seizure onset in bMTLE tends to be in adolescence or adulthood, and patients frequently have a family history of febrile seizures and epilepsy. Long-term seizure freedom is observed with or without antiepileptic medication. On brain MRI, nearly 40% of patients with long-standing bMTLE show evidence of hippocampal sclerosis, a feature usually associated with refractory temporal lobe epilepsy. Prospective studies are needed to determine the features that allow prediction of a benign course, and to clarify the significance of hippocampal MRI changes.
Country: EUA
Editor: Nature Publishing Group
Rights: fechado
Identifier DOI: 10.1038/nrneurol.2010.212
Date Issue: 2011
Appears in Collections:Artigos e Materiais de Revistas Científicas - Unicamp

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