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Type: Artigo de periódico
Title: Availability of olfactory bulb: experience from a British Brain Bank
Author: Rajan, S
Parsons, L
Lees, AJ
Silveira-Moriyama, L
Abstract: The olfactory bulb and tract (OB/OT) are among the earliest structures in the brain to undergo pathological changes in many neurodegenerative conditions. The availability of OB/OT samples from brain specimens in brain banks therefore assumes importance. We collected data from 5 years (2006-2010) regarding the presence or absence of OB/OT material in cases received by the Queen Square Brain Bank (QSBB) for Neurological Disorders, UCL Institute of Neurology, UK, to estimate availability of OB/OT material at the brain bank and also to look for possible associations. Of the 438 cases received, 320 had complete data regarding OB/OT and 29.4% of these had OB/OT in at least one half of the specimen. Unavailability of OB/OT was associated with larger post-mortem delays (p<0.001), suggesting that the delay might render the tissue more friable and hence lead to its loss. Brains from female donors also tended to have a higher availability in our samples.
Subject: olfactory bulb
olfactory tract
brain bank
Parkinson's disease
Country: Brasil
Editor: Assoc Arquivos Neuro- Psiquiatria
Rights: aberto
Date Issue: 2013
Appears in Collections:Artigos e Materiais de Revistas Científicas - Unicamp

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