Please use this identifier to cite or link to this item: http://repositorio.unicamp.br/jspui/handle/REPOSIP/55178
Type: Artigo de periódico
Title: Atypical glandular cells: criteria to discriminate benign from neoplastic lesions and squamous from glandular neoplasia
Author: Torres, JCC
Derchain, SFM
Gontijo, RC
Westin, MCD
Zeferino, LC
Angelo-Andrade, LAL
Rabelo-Santos, SH
Abstract: Objective: Atypical glandular cells: criteria to discriminate benign from neoplastic lesions and squamous from glandular neoplasia Methods: To evaluate the presence of some criteria in cervical smears with atypical glandular cells and their correlation with histological patterns to identify pre-neoplastic and neoplastic lesions. Results: Histological results showed intraepithelial or invasive neoplasia in 35 (48%) cases and benign lesions in 38 (52%) cases. After logistic regression and decision tree analysis an increased nuclear/cytoplasmic ratio and the presence of dyskeratotic cells were strongly associated with intraepithelial or invasive neoplasia and the differential cyto-morphological criteria for glandular lesions were decreased cytoplasm, irregular nuclear membranes and the presence of nucleoli. Conclusion: The analysis of individual cyto-morphological criteria can better predict intraepithelial or invasive neoplasia and differentiate glandular from squamous lesions.
Subject: atypical glandular cells
cervical smear
cyto-morphological criteria
intraepithelial or invasive neoplasia
Country: Inglaterra
Editor: Blackwell Publishing
Rights: fechado
Identifier DOI: 10.1111/j.1365-2303.2005.00300.x
Date Issue: 2005
Appears in Collections:Artigos e Materiais de Revistas Científicas - Unicamp

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