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|Type:||Artigo de periódico|
|Title:||Atypical glandular cells: criteria to discriminate benign from neoplastic lesions and squamous from glandular neoplasia|
|Abstract:||Objective: Atypical glandular cells: criteria to discriminate benign from neoplastic lesions and squamous from glandular neoplasia Methods: To evaluate the presence of some criteria in cervical smears with atypical glandular cells and their correlation with histological patterns to identify pre-neoplastic and neoplastic lesions. Results: Histological results showed intraepithelial or invasive neoplasia in 35 (48%) cases and benign lesions in 38 (52%) cases. After logistic regression and decision tree analysis an increased nuclear/cytoplasmic ratio and the presence of dyskeratotic cells were strongly associated with intraepithelial or invasive neoplasia and the differential cyto-morphological criteria for glandular lesions were decreased cytoplasm, irregular nuclear membranes and the presence of nucleoli. Conclusion: The analysis of individual cyto-morphological criteria can better predict intraepithelial or invasive neoplasia and differentiate glandular from squamous lesions.|
|Subject:||atypical glandular cells|
intraepithelial or invasive neoplasia
|Appears in Collections:||Artigos e Materiais de Revistas Científicas - Unicamp|
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