Please use this identifier to cite or link to this item: http://repositorio.unicamp.br/jspui/handle/REPOSIP/55039
Type: Artigo de periódico
Title: Association between genital intraepithelial lesions and anal squamous intraepithelial lesions in HIV-negative women
Author: Jacyntho, CMA
Giraldo, PC
Horta, AA
Grandelle, R
Goncalves, AK
Fonseca, T
Eleuterio, J
Abstract: OBJECTIVE: The objective of the study was to evaluate the risk of anal squamous intraepithelial lesions (ASILs) in immunocompetent women with genital squamous intraepithelial lesions (GSILs). STUDY DESIGN: This was a cross-sectional study that included 260 immunocompetent women divided into 2 study groups: 1 group included 184 women diagnosed with GSIL by genital colposcopy and biopsy, and the other included 76 controls. All subjects were submitted to anoscopy followed by a biopsy if pertinent. RESULTS: Of 184 GSIL women, 32 (17.4%) had ASIL (P < .001). The risk of ASIL was 13.1 times greater for GSIL women when there were 3 or 4 genital sites involved. All cases of high-grade ASIL were found in women with cervical GSILs. Among risk factors, anal intercourse without a condom demonstrated an important association with ASIL (prevalence ratio adjusted for age = 2.6). CONCLUSION: There seems to be a strong association between ASIL and multicentric GSIL. Another factor related to ASIL was the practice of unprotected anal intercourse.
Subject: anal canal
anus neoplasms
cervical intraepithelial neoplasia
colposcopy
Country: EUA
Editor: Mosby-elsevier
Rights: fechado
Identifier DOI: 10.1016/j.ajog.2011.03.011
Date Issue: 2011
Appears in Collections:Artigos e Materiais de Revistas Científicas - Unicamp

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