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Type: Artigo de periódico
Title: Antitumor, Antimicrobial Effect and Chemical Composition of the Essential Oil of Croton polyandrus Spreng.
Author: Fernandes, HMB
Oliveira, AA
Sousa, JP
Oliveira, TL
Lima, EO
Meireles, DRP
Brito, MT
Zelioli, IAM
Queiroz, NCA
Foglio, MA
Ruiz, ALTG
Carvalho, JE
Silva, MS
Castello-Branco, MVS
Tavares, JF
Abstract: The composition of the essential oil obtained from the dried flowering aerial parts of Croton polyandrus Spreng. was analyzed by GC and GC-MS. The antimicrobial activity of the essential oil was studied using the microdilution method and determination of minimal inhibitory concentration (MIC) value. In vitro antiproliferative activity was evaluated in ten human cancer cell lines and two non-tumor cell lines. Total growth inhibition (TGI) values were chosen to measure antiproliferative activity. Thirty-three components have been identified in the essential oil of Croton polyandrus Spreng. The major constituents of the essential oil were p-cymene (12.4 %), bornyl acetate (11.0 %) and ascaridole (6.4 %). The results obtained with Croton polyandrus Spreng. oil showed a moderate antifungal activity, with MIC equal the 64 mu g/mL for all fungi strains and weak antibacterial activity; cytocidal effect for most of the strains used were tested only at the highest concentration and showed no cytostatic effect.
Subject: Antibacterial activity
Antifungal activity
Antitumor activity
Croton polyandrus
Essential oil
Country: Argentina
Editor: Colegio Farmaceuticos Provincia De Buenos Aires
Citation: Latin American Journal Of Pharmacy. Colegio Farmaceuticos Provincia De Buenos Aires, v. 31, n. 10, n. 1430, n. 1434, 2012.
Rights: fechado
Date Issue: 2012
Appears in Collections:Unicamp - Artigos e Outros Documentos

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