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Type: Artigo de periódico
Title: Antispermatogenic effect of Achillea millefolium L. in mice
Author: Montanari, T
de Carvalho, JE
Dolder, H
Abstract: The effect of an ethanolic extract (200 mg/kg/day, intraperitoneally, for 20 days) and a hydroalcoholic extract (300 mg/kg/day, orally, for 30 days) of Achillea millefolium L. (yarrow) flowers on the spermatogenesis of Swiss mice was studied by evaluating morphologic characteristics with the light and electron microscopes. The alterations observed were exfoliation of immature germ cells, germ cell necrosis, acid seminiferous tubule vacuolization. Animals treated with the extracts had an increased number of metaphases in the germ epithelium that might be due to cytotoxic substances or substances stimulating cell Proliferation. (C) 1998 Elsevier Science Inc. All rights reserved.
Subject: Achillea millefolium
medicinal plants
antispermatogenic agent
male Swiss mice
Country: EUA
Editor: Elsevier Science Inc
Rights: fechado
Identifier DOI: 10.1016/S0010-7824(98)00107-3
Date Issue: 1998
Appears in Collections:Unicamp - Artigos e Outros Documentos

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