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Type: Artigo de periódico
Title: Amyotrophic lateral sclerosis Prospective study on respiratory parameters
Author: Almeida, SRM
Silva, LBC
Guerreiro, CAM
Nucci, A
Abstract: Objective: To verify how efficient respiratory parameters are in the follow-up of subjects with amyotrophic lateral sclerosis (ALS) and to observe possible correlations between respiratory and nutritional functions. Method: Sixteen patients with probable or defined ALS were selected and evaluated over eight months using the following respiratory parameters: spirometry, maximum inspiratory pressure (MIP), maximum expiratory pressure (MEP), arterial gasometry and pulse oximetry; and nutritional parameters such as body mass index (BMI) and percentage weight loss. Results: P(a)CO(2) was a significant parameter to follow up disease evolution (p=0.051). There was significant correlation between MIP and MEP (r: 0.83); BMI and MIP (r: 0.70); BMI and MEP (r: 0.72); pulse oximetry and forced vital capacity (r: 0.57). Conclusion: P(a)CO(2) was shown to be an efficient and significant parameter in the measurement of respiratory impairment; the correlations among MIP, MEP and BMI indicated that these are significant parameters for periodic clinical evaluation.
Subject: amyotrophic lateral sclerosis
maximum inspiratory pressure
maximum expiratory pressure
body mass index
Country: Brasil
Editor: Assoc Arquivos Neuro- Psiquiatria
Citation: Arquivos De Neuro-psiquiatria. Assoc Arquivos Neuro- Psiquiatria, v. 68, n. 2, n. 258, n. 262, 2010.
Rights: aberto
Identifier DOI: 10.1590/S0004-282X2010000200020
Date Issue: 2010
Appears in Collections:Unicamp - Artigos e Outros Documentos

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