Please use this identifier to cite or link to this item: http://repositorio.unicamp.br/jspui/handle/REPOSIP/54120
Type: Artigo de periódico
Title: Acidulated Phosphate Fluoride Application Changes the Protein Composition of Human Acquired Enamel Pellicle
Author: Masson, N
Domingues, RR
Cury, JA
Leme, AFP
Abstract: We evaluated, by proteomic analysis, whether the chemical changes provoked on enamel by acidulated phosphate fluoride (APF) application alter the protein composition of acquired enamel pellicle. Enamel slabs, pretreated with distilled water (negative control), phosphoric acid (active control) or APF solution, were immersed in human saliva for pellicle formation. The adsorbed proteins were extracted and analyzed by liquid chromatography-mass spectrometry/mass spectrometry. Fifty-six proteins were identified, 12 exclusive to APF and 11 to phosphoric acid. APF decreased the concentration of histatin-1, but increased the concentration of S100-A9, which is confirmed by immunoblotting. The findings suggest that APF application changes the acquired enamel pellicle composition. Copyright (C) 2013 S. Karger AG, Basel
Subject: Acidulated phosphate fluoride
Dental pellicle
Mass spectrometry
Proteomics
Country: Suíça
Editor: Karger
Rights: fechado
Identifier DOI: 10.1159/000346280
Date Issue: 2013
Appears in Collections:Artigos e Materiais de Revistas Científicas - Unicamp

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