Please use this identifier to cite or link to this item: http://repositorio.unicamp.br/jspui/handle/REPOSIP/54080
Type: Artigo de periódico
Title: Accuracy of the urinary albumin to creatinine ratio as a predictor of albuminuria in adults with sickle cell disease
Author: Lima, CSP
Bottini, PV
Garlipp, CR
Santos, AO
Costa, FF
Saad, STO
Abstract: Aim: To test the usefulness of a random urine specimen albumin to creatinine ratio (A/C) in predicting 12 hour urinary albumin excretion (12UA) in patients with sickle cell disease. Methods: 12UA and A/C were measured in nocturnal urine collections and random morning urine samples, respectively, of 72 patients with sickle cell disease. Results: The correlation of A/C values with 12UA values did not provide support for the use of random urine specimens for predicting urinary albumin excretion (UAE) in these patients. However, values of A/C greater than or equal to 0.45 and < 0.45 were indicative of raised and normal UAE, respectively, The sensitivity, specificity, and accuracy of the test were 100.0%, 87.2%, and 91.7%, respectively. Conclusions: This method cannot be recommended for predicting 12UA in patients with sickle cell disease, but it is useful for selecting patients who should collect 12 hour urine for the estimation of UAE.
Country: Inglaterra
Editor: British Med Journal Publ Group
Rights: fechado
Identifier DOI: 10.1136/jcp.55.12.973
Date Issue: 2002
Appears in Collections:Unicamp - Artigos e Outros Documentos

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