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Type: Artigo de periódico
Title: Absolute ethanol and 5% ethanolamine oleate are comparable for sclerotherapy of esophageal varices
Author: Meirelles-Santos, JO
Carvalho, AF
Callejas-Neto, F
Magna, LA
Yamanaka, A
Zeitune, JMR
Brandalise, NA
Ferraz, JGP
Abstract: Background: Endoscopic sclerotherapy is widely accepted as an effective treatment for the eradication of esophageal varices in patients with portal hypertension and a history of upper gastrointestinal bleeding. The objective of this study was to assess the effectiveness and safety of absolute ethanol as an alternative sclerosing agent to the commonly used 5% ethanolamine oleate. Methods: One hundred fifty-seven patients with portal hypertension and a history of variceal bleeding were randomly assigned to sclerotherapy with absolute ethanol (n = 66) or 5% ethanolamine oleate (n = 91) between January 1992 and July 1994. Once eradication was achieved, these patients were prospectively followed until September 1998. Results: Sclerotherapy with both sclerosants resulted in similar eradication rates (similar to 90%), with comparable numbers of sessions required for eradication (5.4 and 5.9 sessions for absolute ethanol and 5% ethanolamine oleate, respectively). Similar complication and recurrent bleeding rates were observed among both groups. Conclusion: Sclerotherapy with absolute ethanol is as effective as with 5% ethanolamine oleate in preventing further bleeding in patients with portal hypertension.
Country: EUA
Editor: Mosby, Inc
Rights: fechado
Identifier DOI: 10.1016/S0016-5107(00)70292-6
Date Issue: 2000
Appears in Collections:Artigos e Materiais de Revistas Científicas - Unicamp

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