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|Type:||Artigo de periódico|
|Title:||A reliable ex vivo invasion assay of human reticulocytes by Plasmodium vivax|
|Abstract:||Currently, there are no reliable RBC invasion assays to guide the discovery of vaccines against Plasmodium vivax, the most prevalent malaria parasite in Asia and South America. Here we describe a protocol for an ex vivo P vivax invasion assay that can be easily deployed in laboratories located in endemic countries. The assay is based on mixing enriched cord blood reticulocytes with matured, trypsin-treated P vivax schizonts concentrated from clinical isolates. The reliability of this assay was demonstrated using a large panel of P vivax isolates freshly collected from patients in Thailand. (Blood. 2011;118(13):e74-e81)|
|Editor:||Amer Soc Hematology|
|Appears in Collections:||Artigos e Materiais de Revistas Científicas - Unicamp|
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