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Type: Artigo de periódico
Title: Mast Cells and Ethanol Consumption: Interactions in the Prostate, Epididymis and Testis of UChB Rats
Author: Mendes, LO
Amorim, JPA
Teixeira, GR
Chuffa, LGA
Fioruci, BA
Pimentel, TA
de Mello, W
Padovani, CR
Pereira, S
Martinez, M
Pinheiro, PFF
Oliani, SM
Martinez, FE
Abstract: Problem Alcoholism has reached alarming proportions while fertility rates slowing in populations. The assessment of inflammatory effects with emphasis on the variation of the mast cells comparing ethanol chronic ingestion on reproductive organs deserves attention. Method of study The mast cells were investigated with light microscopy using toluidine blue to locate and count total mast cells and immunohistochemistry to identify the connective tissue mast cells (CTMC). Results The increase in total mast cells in the prostate, total and degranulated mast cells in epididymis of UChB rats was accompanied by a greater proportion of mucosal mast cells (MMC) in these organs. In addition, a lower incidence of degranulated mast cells was observed in epididymis of control rats. Conclusions Ethanol increases the number of total and degranulated mast cells in the prostate and epididymis, as well as associated with increasing MMC, and therefore, it could be leading to inflammation in these organs.
Subject: Epididymis
mast cell
Country: EUA
Editor: Wiley-blackwell
Rights: fechado
Identifier DOI: 10.1111/j.1600-0897.2010.00958.x
Date Issue: 2011
Appears in Collections:Artigos e Materiais de Revistas Científicas - Unicamp

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