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Type: Artigo de periódico
Title: Malignant mixed Mullerian tumor of the uterine cervix with neuroendocrine differentiation
Author: Ribeiro-Silva, A
Novello-Vilar, A
Cunha-Mercante, AM
Andrade, LALD
Abstract: Malignant mixed Mullerian tumors (MMMTs) are rare neoplasms. We report the clinical, pathologic, and immunohistochemical features of an MMMT primary of uterine cervix. This lesion was composed of a poorly differentiated epithelial component (cytokeratin positive) and a spindle cell component (vimentin positive) with heterologous (myoblastic) differentiation (focal 1A4 positive). There were also cells with neuroendocrine features that expressed S-100 and chromogranin A. Along with a brief review of this amazing neoplasm, some histogenetic concepts relevant to this case are discussed. To our knowledge this is the first report of a malignant mixed Mullerian tumor of the uterine cervix with neuroendocrine differentiation.
Subject: cervix
malignant mixed mullerian tumor
Country: EUA
Editor: Blackwell Publishing Inc
Rights: fechado
Identifier DOI: 10.1046/j.1525-1438.2002.01100.x
Date Issue: 2002
Appears in Collections:Unicamp - Artigos e Outros Documentos

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