Please use this identifier to cite or link to this item: http://repositorio.unicamp.br/jspui/handle/REPOSIP/52691
Type: Artigo de periódico
Title: 7-METHYLXANTHINE IS NOT INVOLVED IN CAFFEINE CATABOLISM IN COFFEA-DEWEVREI
Author: MAZZAFERA, P
Abstract: To investigate the role of 7-methylxanthine as an intermediary compound in the degradation of theobromine to xanthine in coffee, leaves and immature fruits of Coffea dewevrei were incubated with [8-H-3]caffeine plus allopurinol. In vivo inhibition of xanthine degradation occurred in fruits and leaves fed with allopurinol since marked incorporation of radioactivity in xanthine and 3-methylxanthine was observed. Nevertheless, HPLC analysis did not reveal any radioactivity in 7-methylxanthine. The results suggest that in coffee theobromine is degraded to xanthine via 3-methylxanthine and 7-methylxanthine is exclusively involved in the caffeine biosynthesis pathway.
Editor: Amer Chemical Soc
Rights: fechado
Identifier DOI: 10.1021/jf00034a002
Date Issue: 1993
Appears in Collections:Unicamp - Artigos e Outros Documentos

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