Please use this identifier to cite or link to this item: http://repositorio.unicamp.br/jspui/handle/REPOSIP/52655
Type: Artigo de periódico
Title: LONG-TERM THERAPY WITH DEFLAZACORT DECREASES MYOCARDIAL FIBROSIS IN mdx MICE
Author: Marques, MJ
Oggiam, DS
Barbin, ICC
Ferretti, R
Neto, HS
Abstract: We evaluated the effects of long-term administration of deflazacort (DFZ) on the progression of myocardial fibrosis in mdx mice. Mdx mice (6 months old) were treated with DFZ for 15 months. Myocardial fibrosis (MF) was evaluated by histomorphometric methods, and treated and untreated mdx mice of the same age (21 months) were compared. DFZ significantly decreased MF We conclude that long-term therapy with DFZ is effective in slowing down the progression of fibrosis in the dystrophin-deficient heart. Muscle Nerve 40: 466-468, 2009
Subject: deflazacort
Duchenne muscular dystrophy
myocardial fibrosis
Country: EUA
Editor: John Wiley & Sons Inc
Rights: fechado
Identifier DOI: 10.1002/mus.21341
Date Issue: 2009
Appears in Collections:Unicamp - Artigos e Outros Documentos

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