Please use this identifier to cite or link to this item: http://repositorio.unicamp.br/jspui/handle/REPOSIP/52580
Type: Artigo de periódico
Title: 2'-FLUOROPOLYNUCLEOTIDE-DIRECTED REVERSE-TRANSCRIPTASE REACTIONS - EFFECT OF HOMOLOGOUS POLYNUCLEOTIDES
Author: JUCA, MB
AOYAMA, H
Abstract: Several homologous polynucleotides have been tested as inhibitors on the reactions catalyzed by avian myeloblastosis virus (AMV) reverse transcriptase, in the presence of polyribonucleotides acid 2'-fluorinated polynucleotides as templates. Polynucleotides differentially inhibited the reactions catalyzed by reverse transcriptase in the presence of these synthetic templates. Polyriboadenylic acid (poly(rA), poly(2'-O-methyladenylic acid) (poly(Am)), poly(2'-fluoro-2'-deoxyadenylic acid) (poly(dAfl), polyinosinic acid (poly(rI)) and polyuridylic acid poly(rU)) inhibited the polyribonucleotide-, but not the 2'-fluorinated polynucleotide-directed reverse transcriptase activity.
Subject: REVERSE TRANSCRIPTASE
2'-FLUOROPOLYNUCLEOLIDES
TEMPLATES
Country: Inglaterra
Editor: Harwood Acad Publ Gmbh
Rights: fechado
Identifier DOI: 10.3109/14756369509020133
Date Issue: 1995
Appears in Collections:Artigos e Materiais de Revistas Científicas - Unicamp

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