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Type: Artigo de periódico
Title: Autoimmune features caused by dengue fever: a case report
Author: Jardim, Denis Leonardo Fontes
Tsukumo, Daniela Miti Lemos
Angerami, Rodrigo N.
Carvalho Filho, Marco Antonio de
Saad, Mário José Abdalla
Abstract: Dengue virus is the most important mosquito-borne viral disease in the world. Co-circulation of the four types of dengue viruses and expansion of dengue epidemic gave rise to infection enhancement and a big expansion of clinical aspects of the disease. Herein we report a case of a 25-year-old white woman with dengue fever and numerous associated autoimmune features. Our patient had proteinuria, an extensive right pleural effusion, a thin pericardial effusion and ascites. She had a low C3 level and positive antinuclear antibody; cryoglobulins were also positive. The numerous autoimmune features of this patient were a diagnostic challenge, since she was a young woman and could be easily mistaken for a rheumatologic patient in a newly open disease. Dengue infection probably was a triggering event causing an abnormal immune response. Therefore, dengue should be suspected in patients with hematological disorders and autoimmune features in endemic regions or those who have travelled to those regions.
Subject: Dengue
Hematologic diseases
Editor: Brazilian Society of Infectious Diseases
Rights: aberto
Identifier DOI: 10.1590/S1413-86702012000100018
Date Issue: 1-Feb-2012
Appears in Collections:Unicamp - Artigos e Outros Documentos

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