Please use this identifier to cite or link to this item: http://repositorio.unicamp.br/jspui/handle/REPOSIP/363229
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dc.contributor.CRUESPUNIVERSIDADE ESTADUAL DE CAMPINASpt_BR
dc.contributor.authorunicampSánchez Romero, Celestept_BR
dc.contributor.authorunicampAlmeida, Oslei Paes dept_BR
dc.typeArtigopt_BR
dc.titleAcute lymphoblastic leukemia/lymphoma of the oral and maxillofacial regionpt_BR
dc.contributor.authorSanchez-Romero, C.pt_BR
dc.contributor.authorPontes, H.A.R.pt_BR
dc.contributor.authorPontes, F.S.C.pt_BR
dc.contributor.authorRocha, A.C.pt_BR
dc.contributor.authorCarlos, R.pt_BR
dc.contributor.authorRendon, J.C.pt_BR
dc.contributor.authorde Almeida, O.P.pt_BR
dc.contributor.authorFonseca, F.P.pt_BR
dc.subjectLeucemiapt_BR
dc.subjectLinfomapt_BR
dc.subjectInfânciapt_BR
dc.subjectOssospt_BR
dc.subject.otherlanguageLeukemiapt_BR
dc.subject.otherlanguageLymphomapt_BR
dc.subject.otherlanguageChildhoodpt_BR
dc.subject.otherlanguageBonespt_BR
dc.description.abstractOur objective was to describe the clinicopathologic and immunohistochemical features of acute lymphoblastic leukemia/lymphoma (ALL/LBL) of the oral and maxillofacial region (OMF). Cases diagnosed as ALL/LBL of the OMF region were retrieved from the files of 2 Brazilian and 1 Guatemalan oral pathology services from 2005 to 2017. Microscopic and immunohistochemical features of each case were reviewed and fully described, and clinical data were retrieved from the pathology reports. During the period considered, 6 cases were identified. Male patients were the most affected (4:2), with a mean age of 19 years old. The mandible was involved in 2 cases, the maxilla in 2, the cheek mucosa in 1, and the parotid gland in 1. Painful swelling was the most common presentation, and 3 patients also had systemic complaints. Microscopically, tumors revealed solid infiltrations of small to medium-sized immature cells. "Puzzle-like" and "starry-sky" patterns were observed, and "single lane" growth was also identified. Immunohistochemically, 2 cases were diagnosed as T-cell ALL/LBL with the leukocyte common antigen (LCA)(+)/cCD3(+)/CD79 a(+)focal/CD20(-)/PAX5(-)/CD99(+)/CD34(-)/CD10(+)/terminal deoxynucleotidyl transferase (TdT)(+) phenotype and 4 as B-cell ALL/LBL with the LCA(+)/CD3(-)/CD20(-)/CD79 a(+)/CD10(+)/CD34 variable/TdT(+) predominant phenotype. The Ki67 index ranged from 80% to 99%. OMF ALL/LBL is rare, but its microscopic features and immunohistochemical profiles CD3(+) or CD79 a(+)CD10(+)/CD34(+)variable/CD99(+)/TDT+ contribute to the correct diagnosispt_BR
dc.relation.ispartofOral surgery, oral medicine, oral pathology and oral radiologypt_BR
dc.relation.ispartofabbreviationOral surg. oral med., oral pathol., oral radiol.pt_BR
dc.publisher.cityAmsterdampt_BR
dc.publisher.countryPaíses Baixospt_BR
dc.publisherElsevierpt_BR
dc.date.issued2018pt_BR
dc.date.monthofcirculationAug.pt_BR
dc.language.isoengpt_BR
dc.description.volume126pt_BR
dc.description.issuenumber2pt_BR
dc.description.firstpage152pt_BR
dc.description.lastpage164pt_BR
dc.rightsFechadopt_BR
dc.sourceWOSpt_BR
dc.identifier.issn2212-4403pt_BR
dc.identifier.eissn2212-4411pt_BR
dc.identifier.eissnFechadopt_BR
dc.identifier.doi10.1016/j.oooo.2018.01.010pt_BR
dc.identifier.urlhttps://www.oooojournal.net/article/S2212-4403(18)30046-4/fulltextpt_BR
dc.description.sponsorshipFUNDAÇÃO DE AMPARO À PESQUISA DO ESTADO DE SÃO PAULO - FAPESPpt_BR
dc.description.sponsorship1FUNDAÇÃO DE AMPARO À PESQUISA DO ESTADO DE SÃO PAULO - FAPESPpt_BR
dc.description.sponsordocumentnumber2017/14880-3pt_BR
dc.date.available2021-06-23T19:48:54Z-
dc.date.accessioned2021-06-23T19:48:54Z-
dc.description.provenanceMade available in DSpace on 2021-06-23T19:48:54Z (GMT). No. of bitstreams: 1 000439067800009.pdf: 9909547 bytes, checksum: 84b8d2ff7ef49e6afcfcf76d03b31929 (MD5) Previous issue date: 2018en
dc.identifier.urihttp://repositorio.unicamp.br/jspui/handle/REPOSIP/363229-
dc.contributor.departmentsem informaçãopt_BR
dc.contributor.departmentDepartamento de Diagnóstico Oralpt_BR
dc.contributor.unidadeFaculdade de Odontologia de Piracicabapt_BR
dc.subject.keywordNumb chin syndromept_BR
dc.subject.keywordOf-the-literaturept_BR
dc.subject.keywordInitial manifestationpt_BR
dc.subject.keywordCavitypt_BR
dc.subject.keywordInvolvementpt_BR
dc.subject.keywordRelapsept_BR
dc.identifier.source000439067800009pt_BR
dc.creator.orcid0000-0001-5365-2692pt_BR
dc.creator.orcid0000-0003-2002-8003pt_BR
dc.type.formArtigopt_BR
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