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Type: Artigo
Title: Prolactin protects against cytokine-induced beta-cell death by NFκB and JNK inhibition
Author: Nardelli, Tarlliza R.
Vanzela, Emerielle C.
Benedicto, Keli C.
Brozzi, Flora
Fujita, André
Cardozo, Alessandra K.
Eizirik, Décio L.
Boschero, Antonio C.
Ortis, Fernanda
Abstract: Type 1 diabetes is caused by an autoimmune assault that induces progressive beta-cell dysfunction and dead. Pro-inflammatory cytokines, such as interleukin 1 beta (IL1B), tumor necrosis factor (TNF) and interferon gamma (IFNG) contribute for beta-cell dea
Subject: NF-kappa B
Proteínas quinases JNK ativadas por mitógeno
Células secretoras de insulina
Fator de transcrição STAT3
Country: Reino Unido
Editor: BioScientifica
Citation: J Mol Endocrinol. 2018 Jul,61(1):25-36. doi: 10.1530/JME-16-0257. Epub 2018 Apr 9.
Rights: Aberto
Identifier DOI: 10.1530/JME-16-0257
Date Issue: 2018
Appears in Collections:IB - Artigos e Outros Documentos

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