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Type: Artigo
Title: Toxic effects of phytol and retinol on human glioblastoma cells are associated with modulation of cholesterol and fatty acid biosynthetic pathways
Author: Facchini, Gustavo
Ignarro, Raffaela Silvestre
Rodrigues-Silva, Erika
Vieira, André Schwambach
Lopes-Cendes, Iscia
Castilho, Roger Frigério
Rogerio, Fabio
Abstract: Glioblastoma (GBM) is the most common primary brain tumor. Genetic mutations may reprogram the metabolism of neoplastic cells. Particularly, alterations in cholesterol and fatty acid biosynthetic pathways may favor biomass synthesis and resistance to ther
Subject: Glioblastoma
Vitamina A
Proteína de ligação a elemento regulador de esterol 1
Ácido graxo sintases
Farnesil-difosfato farnesiltransferase
Country: Estados Unidos
Editor: Springer
Citation: J Neurooncol. 2018 Feb,136(3):435-443. doi: 10.1007/s11060-017-2672-9. Epub 2017 Nov 20.
Rights: Fechado
Identifier DOI: 10.1007/s11060-017-2672-9
Date Issue: 2018
Appears in Collections:IB - Artigos e Outros Documentos

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