Please use this identifier to cite or link to this item: http://repositorio.unicamp.br/jspui/handle/REPOSIP/359
Type: Artigo de periódico
Title: Expression of genes related to muscle plasticity after strength and power training regimens
Author: LAMAS, L.
AOKI, M. S.
UGRINOWITSCH, C.
CAMPOS, G. E. R.
REGAZZINI, M.
MORISCOT, A. S.
TRICOLI, V.
Abstract: The purpose of our study was to compare the effects of 8-week progressive strength and power training regimens on strength gains and muscle plasticity [muscle fiber hypertrophy and phenotype shift, mammalian target of rapamycin (mTOR), regulatory-associated protein of mTOR (RAPTOR), rapamycin-insensitive companion of m-TOR (RICTOR), calcineurin and calcipressin gene expression]. Twenty-nine physically active subjects were divided into three groups: strength training (ST), power training (PT) and control (C). Squat 1 RM and muscle biopsies were obtained before and after the training period. Strength increased similarly for both ST and PT groups (P < 0.001). Fiber types I, IIa and IIb presented hypertrophy main time effect (P < 0.05). Only type IIb percentage decreased from pre- to post-test (main time effect, P < 0.05). mTOR and RICTOR mRNA expression increased similarly from pre- to post-test (P < 0.01). RAPTOR increased after training for both groups (P < 0.0001), but to a greater extent in the ST (P < 0.001) than in the PT group. 4EBP-1 decreased after training when the ST and PT groups were pooled (P < 0.05). Calcineurin levels did not change after training, while calcipressin increased similarly from pre- to post-test (P < 0.01). In conclusion, our data indicate that these training regimens produce similar performance improvements; however, there was a trend toward greater hypertrophy-related gene expression and muscle fiber hypertrophy in the ST group.
Subject: mTOR
RAPTOR
RICTOR
4E-BP1
calcineurin
calcipressin
Country: Estados Unidos
Editor: WILEY-BLACKWELL PUBLISHING, INC
Citation: SCANDINAVIAN JOURNAL OF MEDICINE & SCIENCE IN SPORTS, v.20, n.2, p.216-225, 2010
Rights: fechado
Identifier DOI: 10.1111/j.1600-0838.2009.00905.x
Address: http://dx.doi.org/10.1111/j.1600-0838.2009.00905.x
http://apps.isiknowledge.com/InboundService.do?Func=Frame&product=WOS&action=retrieve&SrcApp=EndNote&UT=000275395400007&Init=Yes&SrcAuth=ResearchSoft&mode=FullRecord
Date Issue: 2010
Appears in Collections:IB - Artigos e Materiais de Revistas Científicas

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