Please use this identifier to cite or link to this item: http://repositorio.unicamp.br/jspui/handle/REPOSIP/357668
Type: Artigo
Title: Stability, purification, and applications of bromelain: A review
Author: de Lencastre Novaes, Leticia Celia
Jozala, Angela Faustino
Lopes, Andre Moreni
Santos-Ebinuma, Valeria de Carvalho
Mazzola, Priscila Gava
Pessoa Junior, Adalberto
Abstract: Bromelain is a cysteine protease found in pineapple tissue. Because of its anti-inflammatory and anti-cancer activities, as well as its ability to induce apoptotic cell death, bromelain has proved useful in several therapeutic areas. The market for this protease is growing, and several studies exploring various properties of this molecule have been reported. This review aims to compile this data, and summarize the main findings on bromelain in the literature to date. The physicochemical properties and stability of bromelain under different conditions are discussed. Several studies on the purification of bromelain from crude extracts using a wide range of techniques such as liquid-liquid extractions by aqueous two-phase system, ultrafiltration, precipitation, and chromatography, have been reported. Finally, the various applications of bromelain are presented. This review therefore covers the main properties of bromelain, aiming to provide an up-to-date compilation of the data reported on this enzyme
Subject: Abacaxi
Country: Estados Unidos
Editor: Wiley
Rights: Fechado
Identifier DOI: 10.1002/btpr.2190
Address: https://aiche.onlinelibrary.wiley.com/doi/full/10.1002/btpr.2190
Date Issue: 2016
Appears in Collections:FCF - Artigos e Outros Documentos

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