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Type: Artigo
Title: Setting research priorities to improve global newborn health and prevent stillbirths by 2025
Author: Yoshida, Sachiyo
Martines, José
Lawn, Joy E.
Wall, Stephen
Souza, Joăo Paulo
Rudan, Igor
Cousens, Simon
The neonatal health research priority setting group
Aaby, Peter
Adam, Ishag
Adhikari, Ramesh Kant
Ambalavanan, Namasivayam
Arifeen, Shams EI
Aryal, Dhana Raj
Asiruddin, Sk
Baqui, Abdullah
Barros, Aluisio JD
Benn, Christine S
Bhandari, Vineet
Bhatnagar, Shinjini
Bhattacharya, Sohinee
Bhutta, Zulfiqar A
Black, Robert E
Blencowe, Hannah
Bose, Carl
Brown, Justin
Bührer, Christoph
Carlo, Wally
Cecatti, Jose Guilherme
Cheung, Po–Yin
Clark, Robert
Colbourn, Tim
Conde–Agudelo, Agustin
Corbett, Erica
Czeizel, Andrew E
Das, Abhik
Day, Louise Tina
Deal, Carolyn
Deorari, Ashok
Dilmen, Uğur
English, Mike
Engmann, Cyril
Esamai, Fabian
Fall, Caroline
Ferriero, Donna M
Gisore, Peter
Hazir, Tabish
Higgins, Rosemary D
Homer, Caroline SE
Hoque, DE
Irgens, Lorentz
Islam, MT
Graft–Johnson, Joseph de
Joshua, Martias Alice
Keenan, William
Khatoon, Soofia
Kieler, Helle
Kramer, Michael S
Lackritz, Eve M
Lavender, Tina
Lawintono, Laurensia
Luhanga, Richard
Marsh, David
McMillan, Douglas
McNamara, Patrick J
Mol, Ben Willem J
Molyneux, Elizabeth
Mukasa, G. K
Mutabazi, Miriam
Nacul, Luis Carlos
Nakakeeto, Margaret
Narayanan, Indira
Olusanya, Bolajoko
Osrin, David
Paul, Vinod
Poets, Christian
Reddy, Uma M
Santosham, Mathuram
Sayed, Rubayet
Schlabritz–Loutsevitch, Natalia E
Singhal, Nalini
Smith, Mary Alice
Smith, Peter G
Soofi, Sajid
Spong, Catherine Y
Sultana, Shahin
Tshefu, Antoinette
Bel, Frank van
Gray, Lauren Vestewig
Waiswa, Peter
Wang, Wei
Williams, Sarah LA
Wright, Linda
Zaidi, Anita
Zhang, Yanfeng
Zhong, Nanbert
Zuniga, Isabel
Bahl, Rajiv
Abstract: In 2013, an estimated 2.8 million newborns died and 2.7 million were stillborn. A much greater number suffer from long term impairment associated with preterm birth, intrauterine growth restriction, congenital anomalies, and perinatal or infectious causes. With the approaching deadline for the achievement of the Millennium Development Goals (MDGs) in 2015, there was a need to set the new research priorities on newborns and stillbirth with a focus not only on survival but also on health, growth and development. We therefore carried out a systematic exercise to set newborn health research priorities for 2013–2025. We used adapted Child Health and Nutrition Research Initiative (CHNRI) methods for this prioritization exercise. We identified and approached the 200 most productive researchers and 400 program experts, and 132 of them submitted research questions online. These were collated into a set of 205 research questions, sent for scoring to the 600 identified experts, and were assessed and scored by 91 experts. Nine out of top ten identified priorities were in the domain of research on improving delivery of known interventions, with simplified neonatal resuscitation program and clinical algorithms and improved skills of community health workers leading the list. The top 10 priorities in the domain of development were led by ideas on improved Kangaroo Mother Care at community level, how to improve the accuracy of diagnosis by community health workers, and perinatal audits. The 10 leading priorities for discovery research focused on stable surfactant with novel modes of administration for preterm babies, ability to diagnose fetal distress and novel tocolytic agents to delay or stop preterm labour. These findings will assist both donors and researchers in supporting and conducting research to close the knowledge gaps for reducing neonatal mortality, morbidity and long term impairment. WHO, SNL and other partners will work to generate interest among key national stakeholders, governments, NGOs, and research institutes in these priorities, while encouraging research funders to support them. We will track research funding, relevant requests for proposals and trial registers to monitor if the priorities identified by this exercise are being addressed.
Subject: Pesquisa
Country: Reino Unido
Editor: Royal Society of Chemistry
Rights: Fechado
Identifier DOI: 10.7189/jogh.06.010508
Date Issue: 2016
Appears in Collections:FCM - Artigos e Outros Documentos

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