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dc.contributor.CRUESPUNIVERSIDADE ESTADUAL DE CAMPINASpt_BR
dc.contributor.authorunicampCury, Jaime Aparecido-
dc.contributor.authorunicampVieira Filho, Waldomiro-
dc.typeArtigopt_BR
dc.titleSensitivity of two biomarkers for biomonitoring exposure to fluoride in children and women: A study in a volcanic areapt_BR
dc.contributor.authorSilva Linhares, Diana Paula-
dc.contributor.authorGarcia, Patricia Ventura-
dc.contributor.authorAmaral, Leslie-
dc.contributor.authorFerreira, Teresa-
dc.contributor.authorCury, Jaime A.-
dc.contributor.authorVieira, Waldomiro-
dc.contributor.authorRodrigues, Armindo dos Santos-
dc.subjectFluoretospt_BR
dc.subject.otherlanguageFluoridespt_BR
dc.description.abstractThe natural enrichment of water with fluoride is related to natural sources such as volcanic activity, with it being documented that fluorosis, an endemic and widespread disease in volcanic areas, is associated to the ingestion of high levels of fluoride through water. Thus, in this study, we aimed to define the fluoride concentration in drinking waters of volcanic origin and compare the sensitivity of urine and nail clip-pings as biomarkers for fluoride exposure in adults and children. Samples of drinking water from four villages in Sao Miguel Island (Azores) were used and the fluoride concentration was determined, as well the fluoride content in urine and toenails clippings from 66 children and 63 adults from these villages. A validated diet questionnaire, assessing sources of fluoride, was recorded for each participant. The fluoride determination in urine and nail clipping samples was made using a fluoride-specific electrode. A positive correlation was found between the fluoride daily intake and fluoride content in children urine (r(s) = 0.475; p < 0.001) and in their nail clippings (r(s) = 0.475; p < 0.001), while in adult women, the fluoride daily intake correlated positively with fluoride content nail clippings (r(s) = 0.495, p < 0.001). This reveals that nail clippings are more reliable as biomarkers of chronic exposure to fluoride than urine for populations of different ages (children vs. adults). Furthermore, nail clippings are more suitable than urine fluoride levels to assess long term exposure to fluoride in areas where the exposure to fluoride in drinking water is considered within, or slightly above, the recommended legal valuespt_BR
dc.relation.ispartofChemospherept_BR
dc.publisher.cityOxfordpt_BR
dc.publisher.countryReino Unidopt_BR
dc.publisherElsevierpt_BR
dc.date.issued2016-
dc.date.monthofcirculationJulypt_BR
dc.language.isoengpt_BR
dc.description.volume155pt_BR
dc.description.firstpage614pt_BR
dc.description.lastpage620pt_BR
dc.rightsFechadopt_BR
dc.sourceWOSpt_BR
dc.identifier.issn0045-6535pt_BR
dc.identifier.eissn1879-1298pt_BR
dc.identifier.doi10.1016/j.chemosphere.2016.04.092pt_BR
dc.identifier.urlhttps://www.sciencedirect.com/science/article/pii/S0045653516305823pt_BR
dc.date.available2021-02-23T14:32:40Z-
dc.date.accessioned2021-02-23T14:32:40Z-
dc.description.provenanceSubmitted by Sanches Olivia (olivias@unicamp.br) on 2021-02-23T14:32:40Z No. of bitstreams: 0. Added 1 bitstream(s) on 2021-05-25T12:08:54Z : No. of bitstreams: 1 000377736100070.pdf: 713862 bytes, checksum: 96759e5b826ebe30e8110db3b217609b (MD5)en
dc.description.provenanceMade available in DSpace on 2021-02-23T14:32:40Z (GMT). No. of bitstreams: 0 Previous issue date: 2016en
dc.identifier.urihttp://repositorio.unicamp.br/jspui/handle/REPOSIP/356330-
dc.contributor.departmentDepartamento de Ciências Fisiológicaspt_BR
dc.contributor.departmentsem informaçãopt_BR
dc.contributor.unidadeFaculdade de Odontologia de Piracicabapt_BR
dc.subject.keywordVolcanismpt_BR
dc.subject.keywordBiomarkerspt_BR
dc.subject.keywordExposurept_BR
dc.subject.keywordDrinking waterpt_BR
dc.identifier.source000377736100070pt_BR
dc.creator.orcid0000-0003-1046-5605pt_BR
dc.creator.orcidsem informaçãopt_BR
dc.type.formArtigopt_BR
dc.description.otherSponsorshipsem informaçãopt_BR
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