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|Title:||Combined training reduces subclinical inflammation in obese middle-age men|
|Author:||Brunelli, Diego T.|
Chacon-Mikahil, Mara Patricia T.
Gaspari, Arthur F.
Lopes, Wendell Arthur
Bonfante, Ivan Luiz P.
Bellotto, Maria Luisa
Libardi, Cleiton Augusto
Cavaglieri, Claudia Regina
|Abstract:||We investigated the effects of 24 wk of combined training on proinflammatory and anti-inflammatory markers associated with obesity in obese middle-age men. Thirty obese men (48.73 1.04 yr; body mass index, 31.00 0.29 kgm(-2)) underwent 24 wk of combined training [CT (N = 17), aerobic (50%-85% of (V) over dot(2peak)) and resistance (6-10 maximum repetition [RM]) training)] three times per week, 60 min per session, or a control group (N = 13). Anthropometric measures, maximal strength for leg press and bench press, peak oxygen uptake ((V) over dotO(2peak)) and serum concentrations of C-reactive protein (CRP), tumor necrosis factor (TNF-), interleukin-6 (IL-6), IL-10, IL-15, resistin, leptin, and adiponectin were determined before (M1) and after 8 (M2), 16 (M3), and 24 (M4) wk of the experimental design. Significant increases were observed in the maximal strength for bench press and leg press, (V) over dotO(2peak), and serum concentrations of adiponectin and IL-15 for CT. Concomitantly, significant decreases were observed in percentage body fat and serum concentrations of CRP, resistin, and leptin for CT after the experimental period. Twenty-four weeks of moderate- to high-intensity CT reduced markers of subclinical inflammation associated with obesity and improved insulin resistance and functional capabilities of obese middle-age men, regardless of dietary intervention and weight loss|
|Subject:||Resistência à insulina|
|Editor:||Lippincott Williams and Wilkins|
|Appears in Collections:||FCM - Artigos e Outros Documentos|
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