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|Title:||Comparison between plasma electrolytic oxidation coating and sandblasted acid-etched surface treatment: histometric, tomographic, and expression levels of osteoclastogenic factors in osteoporotic rats|
|Author:||Momesso, Gustavo Antonio Correia|
Souza Santos, Anderson Maikon de
Fonseca e Santos, João Matheus
Cruz, Nilson Cristino da
Barão, Valentim Adelino Ricardo
Siroma, Rafael Shinoske
Shibli, Jamil Awad
Perez Faverani, Leonardo
|Abstract:||Plasma electrolytic oxidation (PEO) has been a promising surface coating with better mechanical and antimicrobial parameters comparing to conventional treatment surfaces. This study evaluated the peri-implant bone repair using (PEO) surface coatings compared with sandblasted acid (SLA) treatment. For this purpose, 44 Wistar rats were ovariectomized (OVX-22 animals) or underwent simulated surgery (SS-22 animals) and received implants in the tibia with each of the surface coatings. The peri-implant bone subsequently underwent molecular, microstructural, bone turnover, and histometric analysis. Real-time PCR showed a higher expression of osteoprotegerin (OPG), receptor activator of nuclear kappa-B ligand (RANKL), and osteocalcin (OC) proteins in the SLA/OVX and PEO/SS groups (p < 0.05). Computed microtomography, confocal microscopy, and histometry showed similarity between the PEO and SLA surfaces, with a trend toward the superiority of PEO in OVX animals. Thus, PEO surfaces were shown to be promising for enhancing peri-implant bone repair in ovariectomized rats|
|Appears in Collections:||FOP - Artigos e Outros Documentos|
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