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Type: Artigo
Title: Sebaceous hyperplasia: systemic treatment with isotretinoin
Author: Tagliolatto, Sandra
de Avelar Alchorne, Mauricio Mota
Santos Neto, Octavio de Oliveira
Enokihara, Mauro Yoshiaki
Abstract: The study aimed to verify the therapeutic action of isotretinoin in the treatment of sebaceous hyperplasia. During two months, 20 patients with sebaceous hyperplasia took isotretinoin at a dosage of 1mg/kg per day. Their skin lesions were counted and photographed before and after treatment and re-evaluated two years later. The average number of sebaceous hyperplasia lesions before treatment was 24 per patient. At the end of two months of therapy, the number of lesions decreased to 2 per patient. The statistically analyzed data showed a reduction in the number of lesions following isotretinoin use (p < 0.05). Two years after the end of the treatment, the average number of sebaceous hyperplasia lesions was 4 per patient. There were no severe side effects. Thus, the data analysis suggests that isotretinoin is a safe and effective drug for treating the disease under study
Subject: Ensaio clínico
Country: Brasil
Editor: Sociedade Brasileira de Dermatologia
Rights: Aberto
Identifier DOI: 10.1590/abd1806-4841.20153192
Date Issue: 2015
Appears in Collections:FCM - Artigos e Outros Documentos

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