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dc.contributor.authorunicampBelangero, Vera Maria Santoro-
dc.contributor.authorunicampPalma, Lilian Monteiro Pereira-
dc.titleCollaborative brazilian pediatric renal transplant registry (CoBrazPed-RTx): a report from 2004 to 2013pt_BR
dc.contributor.authorGarcia, C.-
dc.contributor.authorGarcia, Cpt_BR
dc.contributor.authorPestana, JMpt_BR
dc.contributor.authorMartins, Spt_BR
dc.contributor.authorNogueira, Ppt_BR
dc.contributor.authorBarros, Vpt_BR
dc.contributor.authorRohde, Rpt_BR
dc.contributor.authorCamargo, Mpt_BR
dc.contributor.authorFeltran, Lpt_BR
dc.contributor.authorEsmeraldo, Rpt_BR
dc.contributor.authorCarvalho, Rpt_BR
dc.contributor.authorSchvartsman, Bpt_BR
dc.contributor.authorVaisbich, Mpt_BR
dc.contributor.authorWatanabe, Apt_BR
dc.contributor.authorCunha, Mpt_BR
dc.contributor.authorMeneses, Rpt_BR
dc.contributor.authorPrates, Lpt_BR
dc.contributor.authorBelangero, Vpt_BR
dc.contributor.authorPalma, Lpt_BR
dc.contributor.authorCarvalho, Dpt_BR
dc.contributor.authorMatuk, Tpt_BR
dc.contributor.authorBenini, Vpt_BR
dc.contributor.authorLaranjo, Spt_BR
dc.contributor.authorAbbud-Filho, Mpt_BR
dc.contributor.authorCharpiot, IMMpt_BR
dc.contributor.authorRamalho, HJpt_BR
dc.contributor.authorLima, Ept_BR
dc.contributor.authorPenido, Jpt_BR
dc.contributor.authorAndrade, Cpt_BR
dc.contributor.authorGesteira, Mpt_BR
dc.contributor.authorTavares, Mpt_BR
dc.contributor.authorPenido, Mpt_BR
dc.contributor.authorDe Souza, Vpt_BR
dc.contributor.authorWagner, Mpt_BR
dc.subjectTransplante de rimpt_BR
dc.subject.otherlanguageKidney transplantationpt_BR
dc.description.abstractThe Collaborative Brazilian Pediatric Renal Transplant Registry started in 2004 as a multicenter initiative aiming to analyze, report, and share the results of pediatric kidney transplantation in Brazil. Data from all pediatric kidney transplants performed between January 2004 and December 2013 were recorded electronically and periodically updated. All patients under 18 years old from the participating centers were enrolled. Demographic data, etiology of chronic kidney disease, and patient and graft survival were analyzed. From a total of 2443 pediatric kidney transplants performed in Brazil during the study period, we report data from 1751 pediatric renal transplants performed in 13 centers enrolled in the collaborative study. Median age at transplantation was 12.4 years, and most of recipients were male (56%). The most common underlying renal etiologies were obstructive uropathy (31%) and glomerulopathy (26%). According to donor source, 1155 (66%) of transplants were performed with deceased donors (DD). Initial immunosuppression consisted mainly of tacrolimus, mycophenolate, steroids, and induction therapy with anti–IL-2R antibodies. One-year graft survival (death-censored) was 93% and 90% (log rank test, P < .01), respectively, for living donor (LD) and DD. Graft losses (15%) were most frequently caused by vascular thrombosis, chronic allograft nephropathy, death with functioning kidney, acute rejection, and recurrent renal disease. Recipients of DD had 2.02 (95% confidence interval: 1.14–3.59) times the hazard of graft loss compared with those of LD (P = .015). Patient survival rates at 1 and 5 years were 98% and 97% for LD and 97% and 93% for DD, respectively. The mortality rate was 3.8%, mainly as the result of infection and cardiovascular disease. The results of this collaborative pediatric transplant study are comparable to international registries. Our effort has been able to maintain an exchange of information, both among the participating centers and with other international registriespt_BR
dc.relation.ispartofTransplantation proceedingspt_BR
dc.relation.ispartofabbreviationTransplant procpt_BR
dc.publisher.cityEstados Unidospt_BR
dc.publisher.countryEstados Unidospt_BR
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dc.contributor.departmentDepartamento de Pediatriapt_BR
dc.contributor.departmentSem informaçãopt_BR
dc.contributor.unidadeFaculdade de Ciências Médicaspt_BR
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