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Type: Artigo
Title: Evaluation of patients with head and neck cancer performing standard treatment in relation to body composition, resting metabolic rate, and inflammatory cytokines
Author: Ridolfi de Carvalho, Thalyta Morandi
Marin, Daniela Miguel
da Silva, Conceicao Aparecida
de Souza, Aglecio Luiz
Talamoni, Maristela
Passos Lima, Carmen Silvia
Alegre, Sarah Monte
Abstract: BackgroundSquamous cell carcinoma of the head and neck (SCCHN) usually emerges as a set of signs and symptoms that, either alone or in combination with standard treatment, may lead to malnutrition and weight loss. MethodsThis study evaluated patients with SCCHN before day 0 and 30 days after the end of treatment, with/without tumor resection. Each individual patient underwent analyses of body composition and resting metabolic rate, as well as assessment of serum glucose, insulin, leptin, adiponectin, interleukin-6 (IL-6), tumor necrosis factor-alpha (TNF-), IL-1, and insulin sensitivity. ResultsThere was body mass loss during treatment and significant reduction in body fat and free fat mass. Early nutritional monitoring and tumor resection before treatment led to a better nutritional status and reduced inflammatory state. ConclusionEarly nutritional monitoring and resection of the tumor by surgery may be important factors for patients to better tolerate treatment
Subject: Caquexia
Country: Estados Unidos
Editor: Wiley
Rights: Fechado
Identifier DOI: 10.1002/hed.23568
Date Issue: 2015
Appears in Collections:FCM - Artigos e Outros Documentos

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