Please use this identifier to cite or link to this item: http://repositorio.unicamp.br/jspui/handle/REPOSIP/354927
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dc.contributor.CRUESPUNIVERSIDADE ESTADUAL DE CAMPINASpt_BR
dc.contributor.authorunicampBarão, Valentim Adelino Ricardo-
dc.typeArtigopt_BR
dc.titleEffect of tyrosol on adhesion of Candida albicans and Candida glabrata to acrylic surfacespt_BR
dc.contributor.authorMonteiro, Douglas Roberto-
dc.contributor.authorFeresin, Leonardo Perina-
dc.contributor.authorArias, Laís Salomão-
dc.contributor.authorBarão, Valentim Adelino Ricardo-
dc.contributor.authorBarbosa, Debora Barros-
dc.contributor.authorDelbem, Alberto Carlos Botazzo-
dc.subjectCandida albicanspt_BR
dc.subject.otherlanguageCandida albicanspt_BR
dc.description.abstractThe prevention of adhesion of Candida cells to acrylic surfaces can be regarded as an alternative to prevent denture stomatitis. The use of quorum sensing molecules, such as tyrosol, could potentially interfere with the adhesion process. Therefore, the aim of this study was to assess the effect of tyrosol on adhesion of single and mixed cultures of Candida albicans and Candida glabrata to acrylic resin surfaces. Tyrosol was diluted in each yeast inoculum (107 cells/ml in artificial saliva) at 25, 50, 100, and 200 mM. Then, each dilution was added to wells of 24-well plates containing the acrylic specimens, and the plates were incubated at 37°C for 2 h. After, the effect of tyrosol was determined by total biomass quantification, metabolic activity of the cells and colony-forming unit counting. Chlorhexidine gluconate (CHG) was used as a positive control. Data were analyzed using analysis of variance (ANOVA) and the Holm–Sidak post hoc test (α = 0.05). The results of total biomass quantification and metabolic activity revealed that the tyrosol promoted significant reductions (ranging from 22.32 to 86.16%) on single C. albicans and mixed cultures. Moreover, tyrosol at 200 mM and CHG significantly reduced (p < 0.05) the number of adhered cells to the acrylic surface for single and mixed cultures of both species, with reductions ranging from 1.74 to 3.64-log10. In conclusion, tyrosol has an inhibitory effect on Candida adhesion to acrylic resin, and further investigations are warranted to clarify its potential against Candida infectionspt_BR
dc.relation.ispartofMedical mycologypt_BR
dc.relation.ispartofabbreviationMed Mycolpt_BR
dc.publisher.cityOxford, OXpt_BR
dc.publisher.countryReino Unidopt_BR
dc.publisherOxford University Presspt_BR
dc.date.issued2015-
dc.date.monthofcirculationSept.pt_BR
dc.language.isoengpt_BR
dc.description.volume53pt_BR
dc.description.issuenumber7pt_BR
dc.description.firstpage656pt_BR
dc.description.lastpage665pt_BR
dc.rightsFechadopt_BR
dc.sourceWOSpt_BR
dc.identifier.issn1369-3786pt_BR
dc.identifier.doi10.1093/mmy/myv052pt_BR
dc.identifier.urlhttps://academic.oup.com/mmy/article/53/7/656/961616pt_BR
dc.description.sponsorshipFUNDAÇÃO DE AMPARO À PESQUISA DO ESTADO DE SÃO PAULO - FAPESPpt_BR
dc.description.sponsordocumentnumber2013/17767–2; 2013/10285–2pt_BR
dc.date.available2021-01-28T21:31:20Z-
dc.date.accessioned2021-01-28T21:31:20Z-
dc.description.provenanceSubmitted by Susilene Barbosa da Silva (susilene@unicamp.br) on 2021-01-28T21:31:20Z No. of bitstreams: 0. Added 1 bitstream(s) on 2021-02-26T13:23:21Z : No. of bitstreams: 1 000361299100002.pdf: 1852972 bytes, checksum: 21a8439d17fc5fca6fe2cc96f4a41248 (MD5)en
dc.description.provenanceMade available in DSpace on 2021-01-28T21:31:20Z (GMT). No. of bitstreams: 0 Previous issue date: 2015en
dc.identifier.urihttp://repositorio.unicamp.br/jspui/handle/REPOSIP/354927-
dc.contributor.departmentDepartamento de Prótese e Periodontiapt_BR
dc.contributor.unidadeFaculdade de Odontologia de Piracicabapt_BR
dc.identifier.source000361299100002pt_BR
dc.creator.orcid0000-0002-6391-9917pt_BR
dc.type.formArtigopt_BR
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