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Type: Outro documento
Title: Tuning the reactivity of Sp1 zinc fingers with platinum complexes
Author: Du, Zhifeng
Paiva, Raphael E. F. de
Qua, Yun
Farrell, Nicholas
Abstract: cis-DDP presents reactivity towards the transcription factor Sp1-F3, as opposed to previous observations for Sp1-F2. Replacing the ammine ligands with the chelating ethylenediamine increases the reactivity giving a unique dinuclear {Pt(en)}2-bis(cysteine)-bridged product, confirmed by study of the binding sequence ACPECP.
Subject: Platina
Country: Reino Unido
Editor: Royal Society of Chemistry
Rights: Fechado
Identifier DOI: 10.1039/c6dt01128d
Date Issue: 2016
Appears in Collections:IQ - Artigos e Outros Documentos

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