Please use this identifier to cite or link to this item: http://repositorio.unicamp.br/jspui/handle/REPOSIP/354837
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dc.contributor.CRUESPUNIVERSIDADE ESTADUAL DE CAMPINASpt_BR
dc.contributor.authorunicampCarvalho, João Ernesto de-
dc.contributor.authorunicampSerain, Alessandra Freitas-
dc.contributor.authorunicampHernández Tasco, Alvaro José-
dc.contributor.authorunicampSalvador, Marcos José-
dc.typeArtigopt_BR
dc.titleChemical composition of the essential oil from the leaves of Anaxagorea brevipes (Annonaceae) and evaluation of its bioactivitypt_BR
dc.contributor.authorAlencar, Danielle Cardoso de-
dc.contributor.authorPinheiro, Maria Lúcia Belém-
dc.contributor.authorPereira, José Lamak da Silva-
dc.contributor.authorCarvalho, João Ernesto de-
dc.contributor.authorCampos, Francinete Ramos-
dc.contributor.authorSerain, Alessandra Freitas-
dc.contributor.authorTirico, Ricardo Brunelli-
dc.contributor.authorHernández-Tasco, Alvaro José-
dc.contributor.authorCosta, Emmanoel Vilaça-
dc.contributor.authorSalvador, Marcos José-
dc.subjectAnnonaceaept_BR
dc.subjectBioatividadept_BR
dc.subjectEssências e óleos essenciaispt_BR
dc.subject.otherlanguageAnnonaceaept_BR
dc.subject.otherlanguageBioactivitypt_BR
dc.subject.otherlanguageEssences and essential oilspt_BR
dc.description.abstractThe essential oil obtained by hydrodistillation from leaves of Anaxagorea brevipes was analysed by gas chromatography fitted with a flame ionisation detector (GC–FID) and coupled to mass spectrometry (GC–MS). Thirty one components were identified, representing around 75.7% of total oil. The major components were β-eudesmol (13.16%), α-eudesmol (13.05%), γ-eudesmol (7.54%), guaiol (5.12%), caryophyllene oxide (4.18%) and β-bisabolene (4.10%). The essential oil showed antimicrobial activity against Gram-positive bacteria and yeast with the MIC values between 25.0 and 100 μg/mL. The highest antiproliferative activity was observed for the oil against MCF-7 (breast, TGI = 12.8 μg/mL), NCI-H460 (lung, TGI = 13.0 μg/mL) and PC-3 (prostate, TGI = 9.6 μg/mL) cell lines, while against no cancer cell line HaCat (keratinocyte) the TGI was 38.8 μg/mL. The oil exhibited a small antioxidant activity assessed through ORAC-FL assay (517 μmol TE/g). This is the first report regarding the chemical composition and bioactivity of A. brevipes essential oil.pt_BR
dc.relation.ispartofNatural product researchpt_BR
dc.relation.ispartofabbreviationNat. prod. res.pt_BR
dc.publisher.cityAbingdonpt_BR
dc.publisher.countryReino Unidopt_BR
dc.publisherTaylor & Francispt_BR
dc.date.issued2016-
dc.date.monthofcirculationMar.pt_BR
dc.language.isoengpt_BR
dc.description.volume30pt_BR
dc.description.issuenumber9pt_BR
dc.description.firstpage1088pt_BR
dc.description.lastpage1092pt_BR
dc.rightsFechadopt_BR
dc.sourceWOSpt_BR
dc.identifier.issn1478-6419pt_BR
dc.identifier.eissn1478-6427pt_BR
dc.identifier.doi10.1080/14786419.2015.1101103pt_BR
dc.identifier.urlhttps://www.tandfonline.com/doi/full/10.1080/14786419.2015.1101103pt_BR
dc.description.sponsorshipCONSELHO NACIONAL DE DESENVOLVIMENTO CIENTÍFICO E TECNOLÓGICO - CNPQpt_BR
dc.description.sponsorshipCOORDENAÇÃO DE APERFEIÇOAMENTO DE PESSOAL DE NÍVEL SUPERIOR - CAPESpt_BR
dc.description.sponsorshipFUNDAÇÃO DE AMPARO À PESQUISA DO ESTADO DA BAHIA - FAPESBpt_BR
dc.description.sponsorshipFUNDAÇÃO DE AMPARO À PESQUISA DO ESTADO DO AMAZONAS - FAPpt_BR
dc.description.sponsordocumentnumberSem informaçãopt_BR
dc.description.sponsordocumentnumberSem informaçãopt_BR
dc.description.sponsordocumentnumberSem informaçãopt_BR
dc.description.sponsordocumentnumberSem informaçãopt_BR
dc.description.sponsordocumentnumberSem informaçãopt_BR
dc.date.available2021-01-27T17:38:08Z-
dc.date.accessioned2021-01-27T17:38:08Z-
dc.description.provenanceSubmitted by Bruna Maria Campos da Cunha (bcampos@unicamp.br) on 2021-01-27T17:38:08Z No. of bitstreams: 0. Added 1 bitstream(s) on 2021-02-19T18:02:07Z : No. of bitstreams: 1 000371931700015.pdf: 571934 bytes, checksum: 213ed575ecff59113483288a13a89749 (MD5)en
dc.description.provenanceMade available in DSpace on 2021-01-27T17:38:08Z (GMT). No. of bitstreams: 0 Previous issue date: 2016en
dc.identifier.urihttp://repositorio.unicamp.br/jspui/handle/REPOSIP/354837-
dc.contributor.departmentSem informaçãopt_BR
dc.contributor.departmentSem informaçãopt_BR
dc.contributor.departmentSem informaçãopt_BR
dc.contributor.departmentDepartamento de Biologia Vegetalpt_BR
dc.contributor.unidadeInstituto de Biologiapt_BR
dc.contributor.unidadeCentro Pluridisciplinar de Pesquisas Químicas, Biológicas e Agrícolaspt_BR
dc.subject.keywordAnaxagorea brevipespt_BR
dc.identifier.source000371931700015pt_BR
dc.creator.orcid0000-0002-6901-6815pt_BR
dc.creator.orcid0000-0002-9810-8057pt_BR
dc.creator.orcid0000-0002-1355-9810pt_BR
dc.creator.orcid0000-0002-3839-5445pt_BR
dc.type.formArtigopt_BR
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