Please use this identifier to cite or link to this item: http://repositorio.unicamp.br/jspui/handle/REPOSIP/354831
Type: Outro documento
Title: Abnormal anal cytology risk in women with known genital squamous intraepithelial lesion
Author: Nobre, Maria do Socorro
Jacyntho, Claudia Marcia
Eleutério Jr, José
Giraldo, Paulo César
Gonçalves, Ana Katherine
Abstract: The purpose of this study was to assess the risk of abnormal anal cytology in women with known genital squamous intraepithelial lesion. This study evaluated 200 women with and without genital squamous intraepithelial lesion who were recruited for anal Pap smears. Women who had abnormal results on equally or over atypical squamous cells of undetermined significance were classified as having abnormal anal cytology. A multiple logistic regression analysis (stepwise) was performed to identify the risk for developing abnormal anal cytology. Data were analyzed using the SPSS 20.0 program. The average age was 41.09 (±12.64). Of the total participants, 75.5% did not practice anal sex, 91% did not have HPV-infected partners, 92% did not have any anal pathology, and 68.5% did not have anal bleeding. More than half (57.5%) had genital SIL and a significant number developed abnormal anal cytology: 13% in the total sample and 17.4% in women with genital SIL. A significant association was observed between genital squamous intraepithelial lesion and anal squamous intraepithelial lesion (PR = 2.46; p = 0.03). In the logistic regression model, women having genital intraepithelial lesion were more likely to have abnormal anal Pap smear (aPR = 2.81; p = 0.02). This report shows that women with genital squamous intraepithelial lesion must be more closely screened for anal cancer.
Subject: Papillomaviridae
Esfregaço vaginal
Country: Reino Unido
Editor: Elsevier
Rights: Aberto
Identifier DOI: 10.1016/j.bjid.2016.01.008
Address: https://www.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702016000300013
Date Issue: 2016
Appears in Collections:FCM - Artigos e Outros Documentos

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