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Type: Artigo
Title: Selective hydrogenation of indolizines: an expeditious approach to derive tetrahydroindolizines and indolizidines from morita–baylis–hillman adducts
Author: Teodoro, Bruno V. M.
Correia, José Tiago M.
Coelho, Fernando
Abstract: In this study, we describe the hydrogenation of indolizines derived from Morita–Baylis–Hillman adducts. We demonstrate that functionalized tetrahydroindolizines and indolizidines can be prepared selectively, at low pressure, by simply adjusting the acidity of the medium. Using this simple and straightforward strategy, substituted tetrahydroindolizines and indolizidines were obtained diastereoselectively in high yield
Subject: Indolizinas
Country: Estados Unidos
Editor: American Chemical Society
Rights: Fechado
Identifier DOI: 10.1021/jo502471q
Date Issue: 2015
Appears in Collections:IQ - Artigos e Outros Documentos

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