Please use this identifier to cite or link to this item: http://repositorio.unicamp.br/jspui/handle/REPOSIP/354500
Type: Artigo
Title: Tamoxifen inhibits the biosynthesis of inositolphosphorylceramide in Leishmania
Author: Trinconi, Cristiana T.
Miguel, Danilo C.
Silber, Ariel M.
Brown, Crhistopher
Mina, John G.M.
Denny, Paul W.
Heise, Norton
Uliana, Silvia R. B.
Abstract: Previous work from our group showed that tamoxifen, an oral drug that has been in use for the treatment of breast cancer for over 40 years, is active both in vitro and in vivo against several species of Leishmania, the etiological agent of leishmaniasis.
Subject: Leishmania amazonensis
Tamoxifeno
Esfingolipídeos
Inositol
Fosfatidilinositóis
Biossíntese
Leishmania amazonensis
Tamoxifen
Sphingolipids
Inositol
Phosphatidylinositols
Biosynthesis
Country: Reino Unido
Editor: Elsevier
Rights: aberto
Identifier DOI: 10.1016/j.ijpddr.2018.10.007
Address: https://www.sciencedirect.com/science/article/pii/S2211320718300691
Date Issue: 2018
Appears in Collections:IB - Artigos e Outros Documentos

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