Please use this identifier to cite or link to this item: http://repositorio.unicamp.br/jspui/handle/REPOSIP/354379
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dc.contributor.CRUESPUNIVERSIDADE ESTADUAL DE CAMPINASpt_BR
dc.contributor.authorunicampGiraldo, Paulo César-
dc.typeArtigopt_BR
dc.titleLiquid‐based cytology and HPV DNA testing using intra‐anal specimens from HIV‐negative women with and without genital HPV‐induced lesionspt_BR
dc.contributor.authorEleutério Jr., José-
dc.contributor.authorBenício, Givanildo Carneiro-
dc.contributor.authorGiraldo, Paulo César-
dc.contributor.authorGonçalves, Ana Katherine Silveira-
dc.contributor.authorEleutério, Renata Mírian Nunes-
dc.contributor.authorOliveira, Denise Nunes-
dc.contributor.authorJacyntho, Cláudia-
dc.subjectTriagempt_BR
dc.subject.otherlanguageScreeningpt_BR
dc.description.abstractScreening for anal cancer using cytology has not been considered in immunocompetent women. The aim of this study was to identify cytological atypia and human papillomavirus (HPV) DNA in intra‐anal specimens from human immunodeficiency virus (HIV)‐negative women with and without genital HPV lesions. Methods This study was a cross‐sectional analysis of 142 women who were negative for the HIV: 80 with genital lesions that were associated with HPV and 62 without HPV‐induced lesions. The women were evaluated at the Federal University of Ceará from October 2011 to June 2012. The statistical analysis included the Fisher exact test and the odds ratio (CI 95%). Results Atypical anal cytology was observed in 24 (29.3%) patients in the study group and in 11 (17.8%) patients in the control group. In cases with at least two sites of HPV‐associated lesions, 12 (41.4%) presented atypical cytology (P = 0.0220; OR = 2.7621, 1.1579–6.5889). When the practice of anal sex was evaluated, atypical cytology was observed in 22/43 (34%) [P = 0.0214; OR = 2.519, 1.146–5.534]. HPV DNA was detected in 17/27 (63%) cases with at least two sites of lesions (P = 0.0293, OR = 2.4855, 1.0960–5.6367). In the 33 cases who presented positive HPV DNA test results, the liquid‐based cytology results were atypical (P = 0.0212, OR = 2.8, 1.1665–6.7208). Conclusion Based on the results, liquid‐based cytology may be used to detect intra‐anal lesions, especially among women who have a history of anal intercourse or who have genital HPV‐associated lesions at multiple sitespt_BR
dc.relation.ispartofDiagnostic cytopathologypt_BR
dc.relation.ispartofabbreviationDiagn. cytopathol.pt_BR
dc.publisher.cityNew York, NYpt_BR
dc.publisher.countryEstados Unidospt_BR
dc.publisherJohn Wiley & Sonspt_BR
dc.date.issued2015-
dc.date.monthofcirculationMaypt_BR
dc.language.isoengpt_BR
dc.description.volume43pt_BR
dc.description.issuenumber5pt_BR
dc.description.firstpage360pt_BR
dc.description.lastpage365pt_BR
dc.rightsFechadopt_BR
dc.sourceWOSpt_BR
dc.identifier.issn8755-1039pt_BR
dc.identifier.eissn1097-0339pt_BR
dc.identifier.doi10.1002/dc.23238pt_BR
dc.identifier.urlhttps://onlinelibrary.wiley.com/doi/full/10.1002/dc.23238pt_BR
dc.description.sponsorshipCONSELHO NACIONAL DE DESENVOLVIMENTO CIENTÍFICO E TECNOLÓGICO - CNPQpt_BR
dc.description.sponsordocumentnumberSem informaçãopt_BR
dc.date.available2021-01-20T20:06:26Z-
dc.date.accessioned2021-01-20T20:06:26Z-
dc.description.provenanceSubmitted by Thais de Brito Barroso (tbrito@unicamp.br) on 2021-01-20T20:06:26Z No. of bitstreams: 0. Added 1 bitstream(s) on 2021-03-08T18:36:57Z : No. of bitstreams: 1 000353222800002.pdf: 233906 bytes, checksum: 887c1542b5081a4eae4c41415bac6587 (MD5)en
dc.description.provenanceMade available in DSpace on 2021-01-20T20:06:26Z (GMT). No. of bitstreams: 0 Previous issue date: 2015en
dc.identifier.urihttp://repositorio.unicamp.br/jspui/handle/REPOSIP/354379-
dc.contributor.departmentDepartamento de Tocoginecologiapt_BR
dc.contributor.unidadeFaculdade de Ciências Médicaspt_BR
dc.subject.keywordAnal cytologypt_BR
dc.subject.keywordHuman papillomaviruspt_BR
dc.subject.keywordHuman papillomavirus DNA testspt_BR
dc.subject.keywordWomenpt_BR
dc.identifier.source000353222800002pt_BR
dc.creator.orcid0000-0003-4365-9879pt_BR
dc.type.formArtigopt_BR
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