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Type: Artigo
Title: Duodenal adenoma surveillance in patients with familial adenomatous polyposis
Author: Campos, Fabio Guilherme
Sulbaran, Marianny
Safatle-Ribeiro, Adriana Vaz
Real Martinez, Carlos Augusto
Abstract: Familial adenomatous polyposis (FAP) is a hereditary disorder caused by Adenomatous Polyposis Gene mutations that lead to the development of colorectal polyps with great malignant risk throughout life. Moreover, numerous extracolonic manifestations incorporate different clinical features to produce varied individual phenotypes. Among them, the occurrence of duodenal adenomatous polyps is considered an almost inevitable event, and their incidence rates increase as a patient's age advances. Although the majority of patients exhibit different grades of duodenal adenomatosis as they age, only a small proportion (1%-5%) of patients will ultimately develop duodenal carcinoma. Within this context, the aim of the present study was to review the data regarding the epidemiology, classification, genetic features, endoscopic features, carcinogenesis, surveillance and management of duodenal polyps in patients with FAP
Subject: Polipose adenomatosa do colo
Country: Estados Unidos
Editor: Baishideng Publishing
Rights: Aberto
Identifier DOI: 10.4253/wjge.v7.i10.950
Date Issue: 2015
Appears in Collections:FCM - Artigos e Outros Documentos

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