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dc.contributor.CRUESPUNIVERSIDADE ESTADUAL DE CAMPINASpt_BR
dc.contributor.authorunicampKimura, Vaneska de Carvalho Melhado-
dc.contributor.authorunicampAlegre, Sarah Monte-
dc.contributor.authorunicampPavin, Elizabeth João-
dc.contributor.authorunicampBahamondes, Luis Guillermo-
dc.contributor.authorunicampFernandes, Arlete Maria dos Santos-
dc.typeArtigopt_BR
dc.titleHigh prevalence of insulin resistance assessed by the glucose clamp technique in hormonal and non-hormonal contraceptive userspt_BR
dc.contributor.authorMelhado-Kimura, Vaneska-
dc.contributor.authorAlegre, Sarah Monte-
dc.contributor.authorPavin, Elizabeth Joao-
dc.contributor.authorSilva dos Santos, Priscilla de Nazare-
dc.contributor.authorBahamondes, Luis-
dc.contributor.authorFernandes, Arlete-
dc.subjectAnticoncepçãopt_BR
dc.subjectResistência à insulinapt_BR
dc.subject.otherlanguageContraceptionpt_BR
dc.subject.otherlanguageInsulin resistancept_BR
dc.description.abstractTo assess the prevalence of insulin resistance (IR) and associated factors in contraceptive users. A total of 47 women 18 to 40 years of age with a body mass index (kg/m(2)) < 30, fasting glucose levels < 100 mg/dl and 2-hour glucose level < 140 mg/dl after a 75-g oral glucose load were submitted to a hyperinsulinemic-euglycemic clamp. The women were distributed in tertiles regarding M-values. The analysed variables were use of combined hormonal/non-hormonal contraception, duration of use, body composition, lipid profile, glucose levels and blood pressure. IR was detected in 19% of the participants. The women with low M-values presented significantly higher body fat mass, waist-to-hip ratio, fasting insulin, HOMA-IR and were nulligravida, showed > 1 year of contraceptive use and higher triglyceride levels. IR was more frequent among combined oral contraceptive users, however no association was observed after regression analysis. The prevalence of IR was high among healthy women attending a family planning clinic independent of the contraceptive method used with possible long-term negative consequences regarding their metabolic and cardiovascular health. Although an association between hormonal contraception and IR could not be found this needs further research. Family planning professionals should be proactive counselling healthy women about the importance of healthy habitspt_BR
dc.relation.ispartofThe european journal of contraception and reproductive health carept_BR
dc.relation.ispartofabbreviationEur. j. contracept. reprod. health carept_BR
dc.publisher.cityAbingdonpt_BR
dc.publisher.countryReino Unidopt_BR
dc.publisherTaylor & Francispt_BR
dc.date.issued2015-
dc.date.monthofcirculationApr.pt_BR
dc.language.isoengpt_BR
dc.description.volume20pt_BR
dc.description.issuenumber2pt_BR
dc.description.firstpage110pt_BR
dc.description.lastpage118pt_BR
dc.rightsFechadopt_BR
dc.sourceWOSpt_BR
dc.identifier.issn1362-5187pt_BR
dc.identifier.eissn1473-0782pt_BR
dc.identifier.doi10.3109/13625187.2014.961599pt_BR
dc.identifier.urlhttps://www.tandfonline.com/doi/full/10.3109/13625187.2014.961599pt_BR
dc.description.sponsorshipFUNDAÇÃO DE AMPARO À PESQUISA DO ESTADO DE SÃO PAULO - FAPESPpt_BR
dc.description.sponsorshipCONSELHO NACIONAL DE DESENVOLVIMENTO CIENTÍFICO E TECNOLÓGICO - CNPQpt_BR
dc.description.sponsordocumentnumberSao Paulo State Health Department (SES-SP) through Research for the National Health Service Initiative, PPSUS, Brazilpt_BR
dc.date.available2021-01-11T14:55:15Z-
dc.date.accessioned2021-01-11T14:55:15Z-
dc.description.provenanceSubmitted by Cintia Oliveira de Moura (cintiaom@unicamp.br) on 2021-01-11T14:55:15Z No. of bitstreams: 0. Added 1 bitstream(s) on 2021-02-19T19:00:02Z : No. of bitstreams: 1 000351398300005.pdf: 172405 bytes, checksum: 164209fb86abd5f40163442090b61335 (MD5)en
dc.description.provenanceMade available in DSpace on 2021-01-11T14:55:15Z (GMT). No. of bitstreams: 0 Previous issue date: 2015en
dc.identifier.urihttp://repositorio.unicamp.br/jspui/handle/REPOSIP/353839-
dc.contributor.departmentsem informaçãopt_BR
dc.contributor.departmentDepartamento de Clínica Médicapt_BR
dc.contributor.departmentDepartamento de Clínica Médicapt_BR
dc.contributor.departmentDepartamento de Tocoginecologiapt_BR
dc.contributor.departmentDepartamento de Tocoginecologiapt_BR
dc.contributor.unidadeFaculdade de Ciências Médicaspt_BR
dc.identifier.source000351398300005pt_BR
dc.creator.orcidsem informaçãopt_BR
dc.creator.orcid0000-0002-8772-9691pt_BR
dc.creator.orcid0000-0002-8678-5579pt_BR
dc.creator.orcid0000-0002-7356-8428pt_BR
dc.creator.orcid0000-0001-5872-0017pt_BR
dc.type.formArtigo de pesquisa originalpt_BR
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