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Type: Artigo
Title: Silencing of P2X7R by RNA interference in the hippocampus can attenuate morphological and behavioral impact of pilocarpine-induced epilepsy
Author: Amorim, Rebeca Padrão
Araujo, Michelle Gasparetti Leão
Valero, Jorge
Lopes-Cendes, Iscia
Pascoal, Vinicius Davila
Malva, Joao Oliveira
Fernandes, Maria Jose da Silva
Abstract: Cell signaling mediated by P2X7 receptors (P2X7R) has been suggested to be involved in epileptogenesis, via modulation of intracellular calcium levels, excitotoxicity, activation of inflammatory cascades, and cell death, among other mechanisms. These proc
Subject: Epilepsia do lobo temporal
Interferência de RNA
Epilepsy, Temporal lobe
RNA Interference
Country: Países Baixos
Editor: Springer
Rights: Fechado
Identifier DOI: 10.1007/s11302-017-9573-4
Date Issue: 2017
Appears in Collections:FCM - Artigos e Outros Documentos

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