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|Title:||In vivo study of novel nanocomposite for prostate cancer treatment|
|Author:||Silveira, C. P.|
Paula, A. J.
Apolinario, L. M.
Favaro, W. J.
|Abstract:||Because of high occurrence of side effects of conventional anticancer drugs, new therapies have been widely studied, such as the use of non-usual molecules and the association with nanomaterials. In this context, sildenafil is a molecule that has been lately considered as a co-adjuvant in cancer therapy because it inhibits an enzyme with a potential role in tumor progression, phosphodiesterase-5. Taking into account the combination of nanoparticles and sildenafil, we produced systems based on mesoporous silica nanoparticles, Pluronic F-127 and sildenafil as the main therapy for prostate cancer|
Neoplasias da próstata
|Appears in Collections:||IB - Artigos e Outros Documentos|
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