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Type: Artigo
Title: In vivo study of novel nanocomposite for prostate cancer treatment
Author: Silveira, C. P.
Paula, A. J.
Apolinario, L. M.
Favaro, W. J.
Duran, N.
Abstract: Because of high occurrence of side effects of conventional anticancer drugs, new therapies have been widely studied, such as the use of non-usual molecules and the association with nanomaterials. In this context, sildenafil is a molecule that has been lately considered as a co-adjuvant in cancer therapy because it inhibits an enzyme with a potential role in tumor progression, phosphodiesterase-5. Taking into account the combination of nanoparticles and sildenafil, we produced systems based on mesoporous silica nanoparticles, Pluronic F-127 and sildenafil as the main therapy for prostate cancer
Subject: Nanocompósitos (Materiais)
Neoplasias da próstata
Country: Reino Unido
Editor: IOP Publishing
Rights: Aberto
Identifier DOI: 10.1088/1742-6596/617/1/012001
Date Issue: 2015
Appears in Collections:IB - Artigos e Outros Documentos

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