Please use this identifier to cite or link to this item: http://repositorio.unicamp.br/jspui/handle/REPOSIP/353233
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dc.contributor.CRUESPUNIVERSIDADE ESTADUAL DE CAMPINASpt_BR
dc.contributor.authorunicampPinto, Roberto Damian Pacheco-
dc.contributor.authorunicampLira, Rodrigo Pessoa Cavalcanti-
dc.contributor.authorunicampAbe, Ricardo Yuji-
dc.contributor.authorunicampFelix, João Paulo Fernandes-
dc.contributor.authorunicampArieta, Carlos Eduardo Leite-
dc.contributor.authorunicampCastro, Rosane Silvestre de-
dc.typeArtigopt_BR
dc.titleDexamethasone/povidone eye drops versus artificial tears for treatment of presumed viral conjunctivitis: a randomized clinical trialpt_BR
dc.contributor.authorPacheco Pinto, Roberto Damian-
dc.contributor.authorCavalcanti Lira, Rodrigo Pessoa-
dc.contributor.authorAbe, Ricardo Yuji-
dc.contributor.authorZacchia, Rafael Santos-
dc.contributor.authorFernandes Felix, Joao Paulo-
dc.contributor.authorFernandes Pereira, Andre Venancio-
dc.contributor.authorLeite Arieta, Carlos Eduardo-
dc.contributor.authorde Castro, Rosane Silvestre-
dc.contributor.authorAlves Bonon, Sandra Helena-
dc.subjectConjuntivitept_BR
dc.subjectAdenoviruspt_BR
dc.subject.otherlanguageAdenovirusespt_BR
dc.subject.otherlanguageConjunctivitispt_BR
dc.description.abstractTo determine whether topical dexamethasone 0.1%/povidone-iodine 0.4% reduces the duration of presumed viral conjunctivitis better than artificial tears and whether the treatment relieves the symptoms of this disease. Randomized, masked and controlled trial. One-hundred twenty-two patients with a clinical diagnosis of presumed viral conjunctivitis were randomized to either the treatment group or the control group. Physicians and patients were masked to the treatment. Swabs were taken from the conjunctival fornix for adenovirus PCR analyses. Patients in the treatment group received topical dexamethasone 0.1%/povidone-iodine 0.4% eye drops four times daily, and patients in the placebo group received artificial tears four times daily, both for seven days. Symptoms were recorded on the day of recruitment and at the time of a follow-up examination 5, 10 and 30 d later. The main outcome was duration of the disease. The others outcomes were overall discomfort, itching, foreign body sensation, tearing, redness, eyelid swelling, side effects of the eye drops, intraocular pressure and the incidence of subepithelial corneal infiltrates. There was no statistically significant difference between the treatment group and the control group in terms of the patients' symptoms, intraocular pressure and incidence of subepithelial cornea infiltrates during the entire follow-up period. Patients of the treatment group reported more stinging (p<0.001) and a shorter conjunctivitis duration (9.4 +/- 4.6 d in the dexamethasone 0.1%/povidone-iodine 0.4% group versus 11.8 +/- 4.9 d in the artificial tears group, p = 0.009). The use of topical dexamethasone 0.1%/povidone-iodine 0.4% eye drops four times daily appears to reduce the duration of conjunctivitis, although it causes more stinging than artificial tearspt_BR
dc.relation.ispartofCurrent eye researchpt_BR
dc.relation.ispartofabbreviationCurr eye respt_BR
dc.publisher.cityAbingdonpt_BR
dc.publisher.countryReino Unidopt_BR
dc.publisherTaylor & Francispt_BR
dc.date.issued2015-
dc.language.isoengpt_BR
dc.description.volume40pt_BR
dc.description.issuenumber9pt_BR
dc.description.firstpage870pt_BR
dc.description.lastpage877pt_BR
dc.rightsAbertopt_BR
dc.sourceWOSpt_BR
dc.identifier.issn0271-3683pt_BR
dc.identifier.eissn1460-2202pt_BR
dc.identifier.doi10.3109/02713683.2014.964419pt_BR
dc.date.available2020-12-17T16:39:50Z-
dc.date.accessioned2020-12-17T16:39:50Z-
dc.description.provenanceSubmitted by Cintia Oliveira de Moura (cintiaom@unicamp.br) on 2020-12-17T16:39:50Z No. of bitstreams: 0. Added 1 bitstream(s) on 2021-06-30T17:36:59Z : No. of bitstreams: 1 000361327200002.pdf: 288836 bytes, checksum: 60e7a4e95ad0aca6803f6581010b3510 (MD5)en
dc.description.provenanceMade available in DSpace on 2020-12-17T16:39:50Z (GMT). No. of bitstreams: 0 Previous issue date: 2015en
dc.identifier.urihttp://repositorio.unicamp.br/jspui/handle/REPOSIP/353233-
dc.contributor.departmentsem informaçãopt_BR
dc.contributor.departmentDepartamento de Oftalmologia e Otorrinolaringologiapt_BR
dc.contributor.departmentsem informaçãopt_BR
dc.contributor.departmentsem informaçãopt_BR
dc.contributor.departmentDepartamento de Oftalmologia e Otorrinolaringologiapt_BR
dc.contributor.departmentsem informaçãopt_BR
dc.contributor.unidadeFaculdade de Ciências Médicaspt_BR
dc.subject.keywordDexamethasonept_BR
dc.subject.keywordPovidone-iodinept_BR
dc.identifier.source000361327200002pt_BR
dc.creator.orcid0000-0002-5541-9672pt_BR
dc.creator.orcidsem informaçãopt_BR
dc.creator.orcid0000-0002-7023-2144pt_BR
dc.creator.orcid0000-0002-1660-8315pt_BR
dc.creator.orcid0000-0003-3175-3147pt_BR
dc.creator.orcid0000-0002-1040-2391pt_BR
dc.type.formArtigopt_BR
dc.description.sponsorNoteOphthalmos S/A, Sao Paulo, Brazilpt_BR
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