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dc.contributor.CRUESPUNIVERSIDADE ESTADUAL DE CAMPINASpt_BR
dc.contributor.authorunicampDella Coletta, Ricardo-
dc.typeArtigopt_BR
dc.titleAssociation between maternal smoking, gender, and cleft lip and palatept_BR
dc.contributor.authorMartelli, Daniella Reis Barbosa-
dc.contributor.authorColetta, Ricardo D.-
dc.contributor.authorOliveira, Eduardo A.-
dc.contributor.authorSwerts, Mário Sérgio Oliveira-
dc.contributor.authorRodrigues, Laíse A. Mendes-
dc.contributor.authorOliveira, Maria Christina-
dc.contributor.authorMartelli Júnior, Hercílio-
dc.subjectFenda labialpt_BR
dc.subject.otherlanguageCleft lippt_BR
dc.description.abstractIntroduction: Cleft lip and/or palate (CL/P) represent the most common congenital anomalies of the face. Objective: To assess the relationship between maternal smoking, gender and CL/P. Methods: This is an epidemiological cross-sectional study. We interviewed 1519 mothers divided into two groups: Cases: mothers of children with CL/P (n = 843) and Controls: mothers of children without CL/P (n = 676). All mothers were classified as smoker or non-smoker subjects during the first trimester of pregnancy. To determine an association among maternal smoking, gender, and CL/P, odds ratios were calculated and the adjustment was made by a logistic regression model. Results: An association between maternal smoking and the presence of cleft was observed. There was also a strong association between male gender and the presence of cleft (OR = 3.51; 95% CI 2.83-4.37). By binary logistic regression analysis, it was demonstrated that both variables were independently associated with clefts. In a multivariate analysis, male gender and maternal smoking had a 2.5- and a 1.5-time greater chance of having a cleft, respectively. Conclusion: Our findings are consistent with a positive association between maternal smoking during pregnancy and CL/P in male gender. The results support the importance of smoking prevention and introduction of cessation programs among women with childbearing potential. © 2015 Associação Brasileira de Otorrinolaringologia e Cirurgia Cérvico-Facialpt_BR
dc.relation.ispartofBrazilian journal of otorhinolaryngologypt_BR
dc.relation.ispartofabbreviationBraz. j. otorhinolaryngolpt_BR
dc.publisher.citySão Paulo, SPpt_BR
dc.publisher.countryBrasilpt_BR
dc.publisherElsevierpt_BR
dc.date.issued2015-
dc.language.isoengpt_BR
dc.description.volume81pt_BR
dc.description.issuenumber5pt_BR
dc.description.firstpage514pt_BR
dc.description.lastpage519pt_BR
dc.rightsAbertopt_BR
dc.sourceSCOPUSpt_BR
dc.identifier.issn1808-8694pt_BR
dc.identifier.eissn1808-8686pt_BR
dc.identifier.doi10.1016/j.bjorl.2015.07.011pt_BR
dc.identifier.urlhttps://linkinghub.elsevier.com/retrieve/pii/S1808869415001020pt_BR
dc.description.sponsorshipCONSELHO NACIONAL DE DESENVOLVIMENTO CIENTÍFICO E TECNOLÓGICO - CNPQpt_BR
dc.description.sponsorshipCOORDENAÇÃO DE APERFEIÇOAMENTO DE PESSOAL DE NÍVEL SUPERIOR - CAPESpt_BR
dc.description.sponsorshipFUNDAÇÃO DE AMPARO À PESQUISA DO ESTADO DE MINAS GERAIS - FAPEMIGpt_BR
dc.description.sponsordocumentnumbersem informaçãopt_BR
dc.date.available2020-11-21T09:43:12Z-
dc.date.accessioned2020-11-21T09:43:12Z-
dc.description.provenanceSubmitted by Sanches Olivia (olivias@unicamp.br) on 2020-11-21T09:43:12Z No. of bitstreams: 0. Added 1 bitstream(s) on 2021-02-11T21:14:42Z : No. of bitstreams: 1 2-s2.0-84942199791.pdf: 452346 bytes, checksum: d7d01dd3e783f7e16d0695eea0a1aa0c (MD5)en
dc.description.provenanceMade available in DSpace on 2020-11-21T09:43:12Z (GMT). No. of bitstreams: 0 Previous issue date: 2015en
dc.identifier.urihttp://repositorio.unicamp.br/jspui/handle/REPOSIP/352870-
dc.contributor.departmentDepartamento de Diagnóstico Oralpt_BR
dc.contributor.unidadeFaculdade de Odontologia de Piracicabapt_BR
dc.subject.keywordCleft lippt_BR
dc.subject.keywordCleft palatept_BR
dc.subject.keywordPregnancypt_BR
dc.subject.keywordSmokingpt_BR
dc.identifier.source2-s2.0-84942199791pt_BR
dc.creator.orcid0000-0001-5285-3046pt_BR
dc.type.formArtigo originalpt_BR
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